Transcriptional Silencing of the Wnt-Antagonist DKK1 by Promoter Methylation Is Associated with Enhanced Wnt Signaling in Advanced Multiple Myeloma

Growth factors in multiple myeloma: a comprehensive analysis of their expression in tumor cells and bone marrow environment using Affymetrix microarrays

(2010) Karène Mahtouk et al.   BMC CANCER

Aurora kinase A is a target of Wnt/ -catenin involved in multiple myeloma disease progression

(2009) J. Dutta-Simmons et al.   BLOOD

Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma

(2009) M. Fulciniti et al.   BLOOD

Wnt-Related Molecules and Signaling Pathway Equilibrium in Hematopoiesis

(2009) Sachin Malhotra et al.   Cell Stem Cell

 -Catenin Small Interfering RNA Successfully Suppressed Progression of Multiple Myeloma in a Mouse Model

(2009) E. Ashihara et al.   CLINICAL CANCER RESEARCH

Multiple myeloma

(2009) Marc S Raab et al.   LANCET

Myeloma-derived Dickkopf-1 disrupts Wnt-regulated osteoprotegerin and RANKL production by osteoblasts: a potential mechanism underlying osteolytic bone lesions in multiple myeloma

(2008) Y.-W. Qiang et al.   BLOOD

The role of Dickkopf-1 in bone development, homeostasis, and disease

(2008) J. J. Pinzone et al.   BLOOD

The pathogenesis of the bone disease of multiple myeloma

(2008) Claire M. Edwards et al.   BONE

Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer

(2008) H Suzuki et al.   BRITISH JOURNAL OF CANCER

Targeting Wnt pathway in lymphoma and myeloma cells

(2008) Matthias Schmidt et al.   BRITISH JOURNAL OF HAEMATOLOGY

Illegitimate WNT Pathway Activation by  -Catenin Mutation or Autocrine Stimulation in T-Cell Malignancies

(2008) R. W.J. Groen et al.   CANCER RESEARCH

Dkk1 and Wnt3 interact to control head morphogenesis in the mouse

(2008) S. L. Lewis et al.   DEVELOPMENT

The canonical Wnt signaling pathway plays an important role in lymphopoiesis and hematopoiesis

(2008) Frank J. T. Staal et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inhibiting Dickkopf-1 (Dkk1) Removes Suppression of Bone Formation and Prevents the Development of Osteolytic Bone Disease in Multiple Myeloma

(2008) Deborah J Heath et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bone marrow microenvironment and the identification of new targets for myeloma therapy

(2008) K Podar et al.   LEUKEMIA

Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma

(2007) Ya-Wei Qiang et al.   BONE

Dickkopf 1 (DKK1) regulates skin pigmentation and thickness by affecting Wnt/β-catenin signaling in keratinocytes

(2007) Yuji Yamaguchi et al.   FASEB JOURNAL