Alterations to Melanocortinergic, GABAergic and Cannabinoid Neurotransmission Associated with Olanzapine-Induced Weight Gain

GABAergic signaling by AgRP neurons prevents anorexia via a melanocortin-independent mechanism

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Metabolic and endocrine adverse effects of second-generation antipsychotics in children and adolescents: A systematic review of randomized, placebo controlled trials and guidelines for clinical practice

(2011) M. De Hert et al.   EUROPEAN PSYCHIATRY

Leptin Action on GABAergic Neurons Prevents Obesity and Reduces Inhibitory Tone to POMC Neurons

(2011) Linh Vong et al.   NEURON

Modeling chronic olanzapine exposure using osmotic minipumps: Pharmacological limitations

(2011) Gary Remington et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Olanzapine-Induced Hyperphagia and Weight Gain Associate with Orexigenic Hypothalamic Neuropeptide Signaling without Concomitant AMPK Phosphorylation

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Olanzapine treatment and metabolic dysfunction: a dose response study in female Sprague Dawley rats

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Direct and Indirect Effects of Cannabinoids on in vitro GABA Release in the Rat Arcuate Nucleus

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A Common Polymorphism in the Cannabinoid Receptor 1 (CNR1) Gene is Associated with Antipsychotic-Induced Weight Gain in Schizophrenia

(2010) Arun K Tiwari et al.   NEUROPSYCHOPHARMACOLOGY

Pro-opiomelanocortin gene transfer to the nucleus of the solitary track but not arcuate nucleus ameliorates chronic diet-induced obesity

(2010) Y. Zhang et al.   NEUROSCIENCE

Potential mechanisms of atypical antipsychotic-induced metabolic derangement: Clues for understanding obesity and novel drug design

(2010) Roberto Coccurello et al.   PHARMACOLOGY & THERAPEUTICS

Role of the endocannabinoid system in food intake, energy homeostasis and regulation of the endocrine pancreas

(2010) Chen Li et al.   PHARMACOLOGY & THERAPEUTICS

The endocannabinoid system, eating behavior and energy homeostasis: The end or a new beginning?

(2010) F.J. Bermudez-Silva et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Repetitive orogastric gavage affects the phenotype of diet-induced obese mice

(2010) Vincent E. de Meijer et al.   PHYSIOLOGY & BEHAVIOR

Obesity Among Those with Mental Disorders

(2009) David B. Allison et al.   AMERICAN JOURNAL OF PREVENTIVE MEDICINE

The role of the endocannabinoid system in the regulation of energy expenditure

(2009) Paul Cavuoto et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

How can antipsychotics cause diabetes mellitus? Insights based on receptor-binding profiles, humoral factors and transporter proteins

(2009) F.C.J. Starrenburg et al.   EUROPEAN PSYCHIATRY

Risperidone Treatment Increases CB1 Receptor Binding in Rat Brain

(2009) Anna Secher et al.   NEUROENDOCRINOLOGY

The endocannabinoid system: Role in glucose and energy metabolism

(2009) Ruben Nogueiras et al.   PHARMACOLOGICAL RESEARCH

Metabolic side effects of antipsychotic drug treatment – pharmacological mechanisms

(2009) Gavin P Reynolds et al.   PHARMACOLOGY & THERAPEUTICS

The role of histaminergic H1 and H3 receptors in food intake: A mechanism for atypical antipsychotic-induced weight gain?

(2009) Chao Deng et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Olanzapine-induced weight gain in the rat: role of 5-HT2C and histamine H1 receptors

(2009) Shona L. Kirk et al.   PSYCHOPHARMACOLOGY

Caudal brainstem delivery of ghrelin induces fos expression in the nucleus of the solitary tract, but not in the arcuate or paraventricular nuclei of the hypothalamus

(2008) Lucy F. Faulconbridge et al.   BRAIN RESEARCH

Olanzapine-induced weight gain: Chronic infusion using osmotic minipumps does not result in stable plasma levels due to degradation of olanzapine in solution

(2008) Esther M. van der Zwaal et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The effects of antipsychotics on the density of cannabinoid receptors in the dorsal vagal complex of rats: implications for olanzapine-induced weight gain

(2008) Katrina Weston-Green et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Endocannabinoids and the Neurochemistry of Gluttony

(2008) Tim Kirkham   JOURNAL OF NEUROENDOCRINOLOGY

Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance

(2008) Qingchun Tong et al.   NATURE NEUROSCIENCE

Pharmacotherapy of Schizophrenic Patients: Preponderance of Off-Label Drug Use

(2008) David Pickar et al.   PLoS One

Short- and long-term effects of antipsychotic drug treatment on weight gain and H1 receptor expression

(2008) Mei Han et al.   PSYCHONEUROENDOCRINOLOGY

Hyperphagia and increased meal size are responsible for weight gain in rats treated sub-chronically with olanzapine

(2008) Nima Davoodi et al.   PSYCHOPHARMACOLOGY

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL