Diet and Energy-Sensing Inputs Affect TorC1-Mediated Axon Misrouting but Not TorC2-Directed Synapse Growth in a Drosophila Model of Tuberous Sclerosis

Phenylketonuria: a 21st century perspective

(2010) Francjan J. van Spronsen   Nature Reviews Endocrinology

Dynamic Switch of Negative Feedback Regulation in Drosophila Akt–TOR Signaling

(2010) Lutz Kockel et al.   PLoS Genetics

Activation of mTORC1 in two steps: Rheb-GTP activation of catalytic function and increased binding of substrates to raptor1

(2009) Joseph Avruch et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The target of rapamycin complex 2 controls dendritic tiling of Drosophila sensory neurons through the Tricornered kinase signalling pathway

(2009) Makiko Koike-Kumagai et al.   EMBO JOURNAL

Cell type specificity of PI3K signaling in Pdk1- and Pten-deficient brains

(2009) N. Chalhoub et al.   GENES & DEVELOPMENT

Autophagy promotes synapse development inDrosophila

(2009) Wei Shen et al.   JOURNAL OF CELL BIOLOGY

The Vam6 GEF Controls TORC1 by Activating the EGO Complex

(2009) Matteo Binda et al.   MOLECULAR CELL

Amino acid regulation of TOR complex 1

(2008) Joseph Avruch et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Tuberous sclerosis complex proteins control axon formation

(2008) Y.-J. Choi et al.   GENES & DEVELOPMENT

Drosophila alicorn Is a Neuronal Maintenance Factor Protecting against Activity-Induced Retinal Degeneration

(2008) M. R. Spasic et al.   JOURNAL OF NEUROSCIENCE

Response of a Neuronal Model of Tuberous Sclerosis to Mammalian Target of Rapamycin (mTOR) Inhibitors: Effects on mTORC1 and Akt Signaling Lead to Improved Survival and Function

(2008) L. Meikle et al.   JOURNAL OF NEUROSCIENCE

Tuberous sclerosis

(2008) Paolo Curatolo et al.   LANCET

Regulation of TORC1 by Rag GTPases in nutrient response

(2008) Eunjung Kim et al.   NATURE CELL BIOLOGY

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

(2008) Y. Sancak et al.   SCIENCE

Role of mTOR in physiology and pathology of the nervous system

(2007) Lukasz Swiech et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS