Elongase Reactions as Control Points in Long-Chain Polyunsaturated Fatty Acid Synthesis

ELOVL2 controls the level of n-6 28:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and sperm maturation in mice

(2010) Damir Zadravec et al.   JOURNAL OF LIPID RESEARCH

Expression of long-chain polyunsaturated fatty acid (LC-PUFA) biosynthesis genes during zebrafish Danio rerio early embryogenesis

(2009) Óscar Monroig et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Cloning and functional characterisation of a fatty acyl elongase from southern bluefin tuna (Thunnus maccoyii)

(2009) Melissa K. Gregory et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Disruption of FADS2 gene in mice impairs male reproduction and causes dermal and intestinal ulceration

(2009) Chad K. Stroud et al.   JOURNAL OF LIPID RESEARCH

An alternate pathway to long-chain polyunsaturates: theFADS2gene product Δ8-desaturates 20:2n-6 and 20:3n-3

(2009) Woo Jung Park et al.   JOURNAL OF LIPID RESEARCH

Docosahexaenoic acid supplementation fully restores fertility and spermatogenesis in male delta-6 desaturase-null mice

(2009) Manuel Roqueta-Rivera et al.   JOURNAL OF LIPID RESEARCH

Highly Unsaturated Fatty Acid Synthesis in Atlantic Salmon: Characterization of ELOVL5- and ELOVL2-like Elongases

(2009) Sofia Morais et al.   MARINE BIOTECHNOLOGY

Δ6-Desaturase (FADS2) deficiency unveils the role of ω3- and ω6-polyunsaturated fatty acids

(2008) Wilhelm Stoffel et al.   EMBO JOURNAL

Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice

(2008) Young-Ah Moon et al.   JOURNAL OF LIPID RESEARCH