Identification of Tumor Suppressors and Oncogenes from Genomic and Epigenetic Features in Ovarian Cancer

Integrated genomic analyses of ovarian carcinoma

(2011) D. Bell et al.   NATURE

Genomics and the Continuum of Cancer Care

(2011) Ultan McDermott et al.   NEW ENGLAND JOURNAL OF MEDICINE

Breast Cancer Methylomes Establish an Epigenomic Foundation for Metastasis

(2011) F. Fang et al.   Science Translational Medicine

Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGM

(2010) Charles J. Vaske et al.   BIOINFORMATICS

The DUB/USP17 deubiquitinating enzymes: A gene family within a tandemly repeated sequence, is also embedded within the copy number variable Beta-defensin cluster

(2010) James F Burrows et al.   BMC GENOMICS

Integrating the multiple dimensions of genomic and epigenomic landscapes of cancer

(2010) Raj Chari et al.   CANCER AND METASTASIS REVIEWS

Copy number alterations in pancreatic cancer identify recurrentPAK4amplification

(2010) Shuaili Chen et al.   CANCER BIOLOGY & THERAPY

Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma

(2010) Houtan Noushmehr et al.   CANCER CELL

Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation

(2010) Maria E. Figueroa et al.   CANCER CELL

Gene Expression: Protein Interaction Systems Network Modeling Identifies Transformation-Associated Molecules and Pathways in Ovarian Cancer

(2010) Sharmila A. Bapat et al.   CANCER RESEARCH

The molecular genetic basis of ovarian cancer and its roadmap towards a better treatment

(2010) E. Despierre et al.   GYNECOLOGIC ONCOLOGY

Proteomics-Based Approach Identified Differentially Expressed Proteins With Potential Roles in Endometrial Carcinoma

(2010) Zhengyu Li et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Breast Cancer Epigenetics: From DNA Methylation to microRNAs

(2010) Jürgen Veeck et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

DNA methylation patterns in luminal breast cancers differ from non-luminal subtypes and can identify relapse risk independent of other clinical variables

(2010) Sitharthan Kamalakaran et al.   Molecular Oncology

The landscape of somatic copy-number alteration across human cancers

(2010) Rameen Beroukhim et al.   NATURE

Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A

(2010) Yaron Pereg et al.   NATURE CELL BIOLOGY

Principles and challenges of genome-wide DNA methylation analysis

(2010) Peter W. Laird   NATURE REVIEWS GENETICS

Genomic instability — an evolving hallmark of cancer

(2010) Simona Negrini et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Automated Network Analysis Identifies Core Pathways in Glioblastoma

(2010) Ethan Cerami et al.   PLoS One

Multi-Platform Whole-Genome Microarray Analyses Refine the Epigenetic Signature of Breast Cancer Metastasis with Gene Expression and Copy Number

(2010) Joseph Andrews et al.   PLoS One

Identification of Candidate Growth Promoting Genes in Ovarian Cancer through Integrated Copy Number and Expression Analysis

(2010) Manasa Ramakrishna et al.   PLoS One

Ovarian Low-grade and High-grade Serous Carcinoma

(2009) Russell Vang et al.   ADVANCES IN ANATOMIC PATHOLOGY

ATAD2 Is a Novel Cofactor for MYC, Overexpressed and Amplified in Aggressive Tumors

(2009) M. Ciro et al.   CANCER RESEARCH

Can molecular biomarker-based patient selection in Phase I trials accelerate anticancer drug development?

(2009) Craig P. Carden et al.   DRUG DISCOVERY TODAY

Protocadherin PCDH10, involved in tumor progression, is a frequent and early target of promoter hypermethylation in cervical cancer

(2009) Gopeshwar Narayan et al.   GENES CHROMOSOMES & CANCER

Epigenetic control

(2009) Geneviève P. Delcuve et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Constitutive activation of signal transducer and activator of transcription 3 in epithelial ovarian carcinoma

(2009) Hao Min et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

A Link between Aurora Kinase and Clp1/Cdc14 Regulation Uncovered by the Identification of a Fission Yeast Borealin-Like Protein

(2009) K. Adam Bohnert et al.   MOLECULAR BIOLOGY OF THE CELL

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

Mechanisms of change in gene copy number

(2009) P. J. Hastings et al.   NATURE REVIEWS GENETICS

Methylation detection oligonucleotide microarray analysis: a high-resolution method for detection of CpG island methylation

(2009) Sitharthan Kamalakaran et al.   NUCLEIC ACIDS RESEARCH

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

The Emerging Role of the RAB25 Small GTPase in Cancer

(2009) Roshan Agarwal et al.   TRAFFIC

Epigenetic Changes in Cancer

(2008) Christine A. Iacobuzio-Donahue   Annual Review of Pathology-Mechanisms of Disease

Cause and Consequences of Genetic and Epigenetic Alterations in Human Cancer

(2008) B. Sadikovic et al.   CURRENT GENOMICS

High-content analysis of cancer genome DNA alterations

(2008) Yan Y Degenhardt et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The cancer biomarker problem

(2008) Charles L. Sawyers   NATURE

PCDH8, the human homolog of PAPC, is a candidate tumor suppressor of breast cancer

(2008) J S Yu et al.   ONCOGENE

Functional Copy-Number Alterations in Cancer

(2008) Barry S. Taylor et al.   PLoS One

Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers

(2008) R. J. Leary et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA