Nuclear-Targeted Deleted in Liver Cancer 1 (DLC1) Is Less Efficient in Exerting Its Tumor Suppressive Activity Both In Vitro and In Vivo

The Small GTPase RhoA Localizes to the Nucleus and Is Activated by Net1 and DNA Damage Signals

(2011) Adi D. Dubash et al.   PLoS One

Akt Phosphorylation of Deleted in Liver Cancer 1 Abrogates Its Suppression of Liver Cancer Tumorigenesis and Metastasis

(2010) Frankie Chi Fat Ko et al.   GASTROENTEROLOGY

DLC-1 as a modulator of proliferation, apoptosis and migration in Burkitt’s lymphoma cells

(2010) Minhua Feng et al.   MOLECULAR BIOLOGY REPORTS

Focal adhesion-localization of START-GAP1/DLC1 is essential for cell motility and morphology

(2009) Katsuhisa Kawai et al.   GENES TO CELLS

DLC1 Activation Requires Lipid Interaction through a Polybasic Region Preceding the RhoGAP Domain

(2009) Patrik Erlmann et al.   MOLECULAR BIOLOGY OF THE CELL

p120Ras-GAP binds the DLC1 Rho-GAP tumor suppressor protein and inhibits its RhoA GTPase and growth-suppressing activities

(2009) X-Y Yang et al.   ONCOGENE

Deleted in Liver Cancer 1 (DLC1) Utilizes a Novel Binding Site for Tensin2 PTB Domain Interaction and Is Required for Tumor-Suppressive Function

(2009) Lo-Kong Chan et al.   PLoS One

Mutations in the Focal Adhesion Targeting Region of Deleted in Liver Cancer-1 Attenuate Their Expression and Function

(2008) Y.-C. Liao et al.   CANCER RESEARCH

DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma

(2008) W. Xue et al.   GENES & DEVELOPMENT

DLC1 interacts with 14-3-3 proteins to inhibit RhoGAP activity and block nucleocytoplasmic shuttling

(2008) R.-P. Scholz et al.   JOURNAL OF CELL SCIENCE

DLC-1 suppresses non-small cell lung cancer growth and invasion by RhoGAP-dependent and independent mechanisms

(2007) Kevin D. Healy et al.   MOLECULAR CARCINOGENESIS