The K+ Channel Opener 1-EBIO Potentiates Residual Function of Mutant CFTR in Rectal Biopsies from Cystic Fibrosis Patients

Targeting CFTR: How to Treat Cystic Fibrosis by CFTR-Repairing Therapies

(2011) Margarida D. Amaral   CURRENT DRUG TARGETS

Cystic fibrosis transmembrane conductance regulator protein repair as a therapeutic strategy in cystic fibrosis

(2010) Peter A Sloane et al.   CURRENT OPINION IN PULMONARY MEDICINE

Disruption of the K+Channel β-Subunit KCNE3 Reveals an Important Role in Intestinal and Tracheal Cl−Transport

(2010) Patricia Preston et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of VX-770 in Persons with Cystic Fibrosis and the G551D-CFTRMutation

(2010) Frank J. Accurso et al.   NEW ENGLAND JOURNAL OF MEDICINE

Intestinal current measurement for diagnostic classification of patients with questionable cystic fibrosis: validation and reference data

(2010) N. Derichs et al.   THORAX

Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

(2009) F. Van Goor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sweat gland bioelectrics differ in cystic fibrosis: a new concept for potential diagnosis and assessment of CFTR function in cystic fibrosis

(2009) T Gonska et al.   THORAX

CFTR Function and Prospects for Therapy

(2008) John R. Riordan   Annual Review of Biochemistry

Cell-Based Fluorescence Screen for K+Channels and Transporters Using an Extracellular Triazacryptand-Based K+Sensor

(2008) Wan Namkung et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effectiveness of PTC124 treatment of cystic fibrosis caused by nonsense mutations: a prospective phase II trial

(2008) Eitan Kerem et al.   LANCET

Physiology and Pathophysiology of Potassium Channels in Gastrointestinal Epithelia

(2008) Dirk Heitzmann et al.   PHYSIOLOGICAL REVIEWS

PTC124 is an orally bioavailable compound that promotes suppression of the human CFTR-G542X nonsense allele in a CF mouse model

(2008) M. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA