Why CCR2 and CCR5 Blockade Failed and Why CCR1 Blockade Might Still Be Effective in the Treatment of Rheumatoid Arthritis

Infiltrated Neutrophils Acquire Novel Chemokine Receptor Expression and Chemokine Responsiveness in Chronic Inflammatory Lung Diseases

(2014) D. Hartl et al.   JOURNAL OF IMMUNOLOGY

Pharmacokinetic and Pharmacodynamic Evaluation of the Novel CCR1 Antagonist CCX354 in Healthy Human Subjects: Implications for Selection of Clinical Dose

(2011) D J Dairaghi et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

CCR5 blockade in rheumatoid arthritis: a randomised, double-blind, placebo-controlled clinical trial

(2010) A. W. R. van Kuijk et al.   ANNALS OF THE RHEUMATIC DISEASES

Preclinical and clinical investigation of a CCR5 antagonist, AZD5672, in patients with rheumatoid arthritis receiving methotrexate

(2010) Daniëlle M. Gerlag et al.   ARTHRITIS AND RHEUMATISM

CCR1 Antagonists: What Have We Learned From Clinical Trials

(2010) Ronald P. Gladue et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Histone Deacetylase Inhibitors Suppress Inflammatory Activation of Rheumatoid Arthritis Patient Synovial Macrophages and Tissue

(2010) Aleksander M. Grabiec et al.   JOURNAL OF IMMUNOLOGY

MLN3897 plus methotrexate in patients with rheumatoid arthritis: Safety, efficacy, pharmacokinetics, and pharmacodynamics of an oral CCR1 antagonist in a phase IIa, double-blind, placebo-controlled, randomized, proof-of-concept study

(2009) Clarissa E. Vergunst et al.   ARTHRITIS AND RHEUMATISM

The dynamics of macrophage lineage populations in inflammatory and autoimmune diseases

(2009) John A. Hamilton et al.   ARTHRITIS AND RHEUMATISM

Chemokine receptor antagonists: part 2

(2009) James E Pease et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Chemokine receptor antagonists: Part 1

(2009) James E Pease et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Monocyte Scintigraphy in Rheumatoid Arthritis: The Dynamics of Monocyte Migration in Immune-Mediated Inflammatory Disease

(2009) Rogier M. Thurlings et al.   PLoS One

Is CCR2 the right chemokine receptor to target in rheumatoid arthritis?

(2008) Amanda E. I. Proudfoot   ARTHRITIS AND RHEUMATISM

Modulation of CCR2 in rheumatoid arthritis: A double‐blind, randomized, placebo‐controlled clinical trial

(2008) Clarissa E. Vergunst et al.   ARTHRITIS AND RHEUMATISM