Molecular Determinants of Interactions between the N-Terminal Domain and the Transmembrane Core That Modulate hERG K+ Channel Gating
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Title
Molecular Determinants of Interactions between the N-Terminal Domain and the Transmembrane Core That Modulate hERG K+ Channel Gating
Authors
Keywords
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Journal
PLoS One
Volume 6, Issue 9, Pages e24674
Publisher
Public Library of Science (PLoS)
Online
2011-09-16
DOI
10.1371/journal.pone.0024674
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Note: Only part of the references are listed.- Demonstration of Physical Proximity between the N Terminus and the S4-S5 Linker of the Humanether-à-go-go-related Gene (hERG) Potassium Channel
- (2011) Pilar de la Peña et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- hERG potassium channel gating is mediated by N- and C-terminal region interactions
- (2011) Ahleah S. Gustina et al. JOURNAL OF GENERAL PHYSIOLOGY
- Structural biology: Breaking the protein rules
- (2011) Tanguy Chouard NATURE
- The N–Terminal Tail of hERG Contains an Amphipathic α–Helix That Regulates Channel Deactivation
- (2011) Chai Ann Ng et al. PLoS One
- NMR solution structure of the N-terminal domain of hERG and its interaction with the S4–S5 linker
- (2010) Qingxin Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Understanding protein non-folding
- (2010) Vladimir N. Uversky et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Mutations within the S4–S5 Linker Alter Voltage Sensor Constraints in hERG K+ Channels
- (2010) Aaron C. Van Slyke et al. BIOPHYSICAL JOURNAL
- Mechanistic Insight into Humanether-à-go-go-related Gene (hERG) K+Channel Deactivation Gating from the Solution Structure of the EAG Domain
- (2010) Frederick W. Muskett et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HERG1 channelopathies
- (2009) Michael C. Sanguinetti PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- A recombinant N-terminal domain fully restores deactivation gating in N-truncated and long QT syndrome mutant hERG potassium channels
- (2009) A. S. Gustina et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- FRET with multiply labeled HERG K+ channels as a reporter of the in vivo coarse architecture of the cytoplasmic domains
- (2008) Pablo Miranda et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Thermodynamic and Kinetic Properties of Amino-Terminal and S4-S5 Loop HERG Channel Mutants under Steady-State Conditions
- (2008) Carlos Alonso-Ron et al. BIOPHYSICAL JOURNAL
- Targeting Ion Channels in Cancer: A Novel Frontier in Antineoplastic Therapy
- (2008) A. Arcangeli et al. CURRENT MEDICINAL CHEMISTRY
- Participation of HERG channel cytoplasmic structures on regulation by the G protein-coupled TRH receptor
- (2008) Carlos Alonso-Ron et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- The hERG K+ channel: target and antitarget strategies in drug development
- (2008) Emanuel Raschi et al. PHARMACOLOGICAL RESEARCH
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