A Phase IIA Randomized Clinical Trial of a Multiclade HIV-1 DNA Prime Followed by a Multiclade rAd5 HIV-1 Vaccine Boost in Healthy Adults (HVTN204)
Published 2011 View Full Article
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Title
A Phase IIA Randomized Clinical Trial of a Multiclade HIV-1 DNA Prime Followed by a Multiclade rAd5 HIV-1 Vaccine Boost in Healthy Adults (HVTN204)
Authors
Keywords
T cells, Vaccines, Cytotoxic T cells, Enzyme-linked immunoassays, Antibodies, Antibody response, Cytokines, HIV-1
Journal
PLoS One
Volume 6, Issue 8, Pages e21225
Publisher
Public Library of Science (PLoS)
Online
2011-08-04
DOI
10.1371/journal.pone.0021225
References
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- Viral Inhibition Assay: A CD8 T Cell Neutralization Assay for Use in Clinical Trials of HIV‐1 Vaccine Candidates
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- Phenotypic and Functional Profile of HIV-Inhibitory CD8 T Cells Elicited by Natural Infection and Heterologous Prime/Boost Vaccination
- (2010) S. A. Freel et al. JOURNAL OF VIROLOGY
- Priming Immunization with DNA Augments Immunogenicity of Recombinant Adenoviral Vectors for Both HIV-1 Specific Antibody and T-Cell Responses
- (2010) Richard A. Koup et al. PLoS One
- Safety and Immunogenicity Study of Multiclade HIV-1 Adenoviral Vector Vaccine Alone or as Boost following a Multiclade HIV-1 DNA Vaccine in Africa
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- (2009) C. Cheng et al. JOURNAL OF VIROLOGY
- Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand
- (2009) Supachai Rerks-Ngarm et al. NEW ENGLAND JOURNAL OF MEDICINE
- International epidemiology of human pre-existing adenovirus (Ad) type-5, type-6, type-26 and type-36 neutralizing antibodies: Correlates of high Ad5 titers and implications for potential HIV vaccine trials
- (2009) T. Christopher Mast et al. VACCINE
- Initial B-Cell Responses to Transmitted Human Immunodeficiency Virus Type 1: Virion-Binding Immunoglobulin M (IgM) and IgG Antibodies Followed by Plasma Anti-gp41 Antibodies with Ineffective Control of Initial Viremia
- (2008) G. D. Tomaras et al. JOURNAL OF VIROLOGY
- HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case–cohort analysis
- (2008) M Juliana McElrath et al. LANCET
- Recent advances in the characterization of HIV-1 neutralization assays for standardized evaluation of the antibody response to infection and vaccination
- (2008) Victoria R. Polonis et al. VIROLOGY
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