Effect of Hydrophobic Mutations in the H2-H3 Subdomain of Prion Protein on Stability and Conversion In Vitro and In Vivo

Globular Domain of the Prion Protein Needs to Be Unlocked by Domain Swapping to Support Prion Protein Conversion

(2011) Iva Hafner-Bratkovič et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disulfide mapping reveals the domain swapping as the crucial process of the structural conversion of prion protein

(2011) Iva Hafner-Bratkovič et al.   Prion

Recombinant prion protein induces a new transmissible prion disease in wild-type animals

(2010) Natallia Makarava et al.   ACTA NEUROPATHOLOGICA

Tetracysteine-tagged prion protein allows discrimination between the native and converted forms

(2010) Jernej Gašperšič et al.   FEBS Journal

PRNP allelic series from 19 years of prion protein gene sequencing at the MRC Prion Unit

(2010) Jon A. Beck et al.   HUMAN MUTATION

Mammalian Prions Generated from Bacterially Expressed Prion Protein in the Absence of Any Mammalian Cofactors

(2010) Jae-Il Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathogenic Mutations in the Hydrophobic Core of the Human Prion Protein Can Promote Structural Instability and Misfolding

(2010) Marc W. van der Kamp et al.   JOURNAL OF MOLECULAR BIOLOGY

Generating a Prion with Bacterially Expressed Recombinant Prion Protein

(2010) F. Wang et al.   SCIENCE

Structural Insights into Alternate Aggregated Prion Protein Forms

(2009) Maurizio Polano et al.   JOURNAL OF MOLECULAR BIOLOGY

The Same Primary Structure of the Prion Protein Yields Two Distinct Self-propagating States

(2008) Natallia Makarava et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of prion protein assembly into amyloid

(2008) J. Stohr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA