The Phenotypic Radiation Resistance of CD44+/CD24−or low Breast Cancer Cells Is Mediated through the Enhanced Activation of ATM Signaling

The CD44+/CD24− phenotype relates to ‘triple-negative’ state and unfavorable prognosis in breast cancer patients

(2010) Alexandra Giatromanolaki et al.   MEDICAL ONCOLOGY

The ATM Inhibitor KU-55933 Suppresses Cell Proliferation and Induces Apoptosis by Blocking Akt In Cancer Cells with Overactivated Akt

(2010) Y. Li et al.   MOLECULAR CANCER THERAPEUTICS

Permanently Blocked Stem Cells Derived From Breast Cancer Cell Lines

(2010) Gangadharan B. Sajithlal et al.   STEM CELLS

Stem cell marker aldehyde dehydrogenase 1-positive breast cancers are characterized by negative estrogen receptor, positive human epidermal growth factor receptor type 2, and high Ki67 expression

(2009) Koji Morimoto et al.   CANCER SCIENCE

Radiation Response of Cancer Stem-Like Cells From Established Human Cell Lines After Sorting for Surface Markers

(2009) Osama Al-Assar et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Reversibility of Epithelial-Mesenchymal Transition (EMT) Induced in Breast Cancer Cells by Activation of Urokinase Receptor-dependent Cell Signaling

(2009) Minji Jo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Treatment Resistance in Stem Cells and Breast Cancer

(2009) Bhuvanesh Dave et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion

(2009) S. E. Golding et al.   MOLECULAR CANCER THERAPEUTICS

Association of reactive oxygen species levels and radioresistance in cancer stem cells

(2009) Maximilian Diehn et al.   NATURE

Phosphorylation of ATM by Cdk5 mediates DNA damage signalling and regulates neuronal death

(2009) Bo Tian et al.   NATURE CELL BIOLOGY

Therapeutic Implications of the Cancer Stem Cell Hypothesis

(2009) Maximilian Diehn et al.   SEMINARS IN RADIATION ONCOLOGY

Cancer Stem Cells and Tumor Response to Therapy: Current Problems and Future Prospects

(2009) Luka Milas et al.   SEMINARS IN RADIATION ONCOLOGY

Breast cancer chemoresistance: Emerging importance of cancer stem cells

(2009) Suebwong Chuthapisith et al.   SURGICAL ONCOLOGY-OXFORD

Transient Inhibition of ATM Kinase Is Sufficient to Enhance Cellular Sensitivity to Ionizing Radiation

(2008) M. D. Rainey et al.   CANCER RESEARCH

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Epithelial mesenchymal transition traits in human breast cancer cell lines

(2008) T. Blick et al.   CLINICAL & EXPERIMENTAL METASTASIS

Stem Cell–Related “Self-Renewal” Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma

(2008) Anastasia Murat et al.   JOURNAL OF CLINICAL ONCOLOGY

Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer

(2008) Martin F. Lavin   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of CD133-Positive Radioresistant Cells in Atypical Teratoid/ Rhabdoid Tumor

(2008) Shih-Hwa Chiou et al.   PLoS One