Effects of Clinically Relevant MPL Mutations in the Transmembrane Domain Revealed at the Atomic Level through Computational Modeling

Tilt and Azimuthal Angles of a Transmembrane Peptide: A Comparison between Molecular Dynamics Calculations and Solid-State NMR Data of Sarcolipin in Lipid Membranes

(2009) Lei Shi et al.   BIOPHYSICAL JOURNAL

The Juxtamembrane Region of EGFR Takes Center Stage

(2009) Stevan R. Hubbard   CELL

Mechanism for Activation of the EGF Receptor Catalytic Domain by the Juxtamembrane Segment

(2009) Natalia Jura et al.   CELL

Threshold Occupancy and Specific Cation Binding Modes in the Hammerhead Ribozyme Active Site are Required for Active Conformation

(2009) Tai-Sung Lee et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural effects of clinically observed mutations in JAK2 exons 13-15: comparison with V617F and exon 12 mutations

(2009) Tai-Sung Lee et al.   BMC STRUCTURAL BIOLOGY

Characterization of 35 new cases with four different MPLW515 mutations and essential thrombocytosis or primary myelofibrosis

(2008) S. Schnittger et al.   HAEMATOLOGICA

New mutations of MPL in primitive myelofibrosis: only the MPL W515 mutations promote a G1/S-phase transition

(2008) R Chaligné et al.   LEUKEMIA

JAK2 and MPL mutations in myeloproliferative neoplasms: discovery and science

(2008) O Kilpivaara et al.   LEUKEMIA

JAKandMPLmutations in myeloid malignancies

(2008) Ayalew Tefferi   LEUKEMIA & LYMPHOMA

Transmembrane Helix Tilting: Insights from Calculating the Potential of Mean Force

(2008) Jinhyuk Lee et al.   PHYSICAL REVIEW LETTERS