Catalytic Mechanism Investigation of Lysine-Specific Demethylase 1 (LSD1): A Computational Study

Molecular Mimicry and Ligand Recognition in Binding and Catalysis by the Histone Demethylase LSD1-CoREST Complex

(2011) Riccardo Baron et al.   STRUCTURE

A lysine conserved in the monoamine oxidase family is involved in oxidation of the reduced flavin in mouse polyamine oxidase

(2010) Michelle Henderson Pozzi et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Importance of a Serine Proximal to the C(4a) and N(5) Flavin Atoms for Hydride Transfer in Choline Oxidase

(2010) Hongling Yuan et al.   BIOCHEMISTRY

Demethylation of RB Regulator MYPT1 by Histone Demethylase LSD1 Promotes Cell Cycle Progression in Cancer Cells

(2010) H.-S. Cho et al.   CANCER RESEARCH

The SNAG domain of Snail1 functions as a molecular hook for recruiting lysine-specific demethylase 1

(2010) Yiwei Lin et al.   EMBO JOURNAL

LSD1 is required for chromosome segregation during mitosis

(2010) Shuang Lv et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Conversion of Mouse Epiblast Stem Cells to an Earlier Pluripotency State by Small Molecules

(2010) Hongyan Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone Demethylase LSD1 Regulates Adipogenesis

(2010) Melina M. Musri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Investigation of the Catalytic Mechanism of Sir2 Enzyme with QM/MM Approach: SN1 vs SN2?

(2010) Zhongjie Liang et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Lysine-Specific Demethylase 1 Regulates the Embryonic Transcriptome and CoREST Stability

(2010) C. T. Foster et al.   MOLECULAR AND CELLULAR BIOLOGY

Oxidation of amines by flavoproteins

(2009) Paul F. Fitzpatrick   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

pH Dependence of a Mammalian Polyamine Oxidase: Insights into Substrate Specificity and the Role of Lysine 315†

(2009) Michelle Henderson Pozzi et al.   BIOCHEMISTRY

Use of pH and Kinetic Isotope Effects To Establish Chemistry as Rate-Limiting in Oxidation of a Peptide Substrate by LSD1

(2009) Helena Gaweska et al.   BIOCHEMISTRY

Mechanistic Studies ofpara-SubstitutedN,N′-Dibenzyl-1,4-diaminobutanes as Substrates for a Mammalian Polyamine Oxidase

(2009) Michelle Henderson Pozzi et al.   BIOCHEMISTRY

Lysine-Specific Demethylase 1 Is Strongly Expressed in Poorly Differentiated Neuroblastoma: Implications for Therapy

(2009) J. H. Schulte et al.   CANCER RESEARCH

Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology

(2009) Soyoung Lim et al.   CARCINOGENESIS

LSD1 Is a Subunit of the NuRD Complex and Targets the Metastasis Programs in Breast Cancer

(2009) Yan Wang et al.   CELL

New roles of flavoproteins in molecular cell biology: Histone demethylase LSD1 and chromatin

(2009) Federico Forneris et al.   FEBS Journal

Cyclical Chromatin Looping and Transcription Factor Association on the Regulatory Regions of the p21 (CDKN1A) Gene in Response to 1α,25-Dihydroxyvitamin D3

(2009) Anna Saramäki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis

(2009) X. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The pH dependence of kinetic isotope effects in monoamine oxidase A indicates stabilization of the neutral amine in the enzyme-substrate complex

(2008) Rachel V. Dunn et al.   FEBS Journal

p53-Targeted LSD1 Functions in Repression of Chromatin Structure and Transcription In Vivo

(2008) W.-W. Tsai et al.   MOLECULAR AND CELLULAR BIOLOGY

The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

(2008) Jing Wang et al.   NATURE GENETICS