Blockade of Gap Junction Hemichannel Suppresses Disease Progression in Mouse Models of Amyotrophic Lateral Sclerosis and Alzheimer's Disease

Motor neuron disease: systematic reviews of treatment for ALS and SMA

(2010) R. W. Orrell   BRITISH MEDICAL BULLETIN

Synergistic Effects of Long-Term Antioxidant Diet and Behavioral Enrichment on  -Amyloid Load and Non-Amyloidogenic Processing in Aged Canines

(2010) V. Pop et al.   JOURNAL OF NEUROSCIENCE

Microglia Activated with the Toll-Like Receptor 9 Ligand CpG Attenuate Oligomeric Amyloid β Neurotoxicity in in Vitro and in Vivo Models of Alzheimer’s Disease

(2009) Yukiko Doi et al.   AMERICAN JOURNAL OF PATHOLOGY

Pre-symptomatic detection of chronic motor deficits and genotype prediction in congenic B6.SOD1G93A ALS mouse model

(2009) C.R. Hayworth et al.   NEUROSCIENCE

Properties of gap junction blockers and their behavioural, cognitive and electrophysiological effects: Animal and human studies

(2009) Grzegorz R. Juszczak et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Blockade of Glutamate Release from Microglia Attenuates Experimental Autoimmune Encephalomyelitis in Mice

(2009) Jin Shijie et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Excitatory amino acid transporter expression by astrocytes is neuroprotective against microglial excitotoxicity

(2008) Jianfeng Liang et al.   BRAIN RESEARCH

Blockade of microglial glutamate release protects against ischemic brain injury

(2008) Hideyuki Takeuchi et al.   EXPERIMENTAL NEUROLOGY

A strategy for developing effective amyotropic lateral sclerosis pharmacotherapy: from clinical trials to novel pharmacotherapeutic strategies

(2008) Masahiko Yamamoto et al.   EXPERT OPINION ON PHARMACOTHERAPY

Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

(2008) Clive Holmes et al.   LANCET

Macrophage-induced neurotoxicity is mediated by glutamate and attenuated by glutaminase inhibitors and gap junction inhibitors

(2008) Izumi Yawata et al.   LIFE SCIENCES

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

(2008) Koji Yamanaka et al.   NATURE NEUROSCIENCE

Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function

(2003) Steven W. Barger et al.   JOURNAL OF NEUROCHEMISTRY