Contribution of Cytochrome P450 and ABCB1 Genetic Variability on Methadone Pharmacokinetics, Dose Requirements, and Response

Title
Contribution of Cytochrome P450 and ABCB1 Genetic Variability on Methadone Pharmacokinetics, Dose Requirements, and Response
Authors
Keywords
Drug metabolism, Blood plasma, Opioids, Enzyme metabolism, Genetic polymorphism, Alleles, Drug therapy, Variant genotypes
Journal
PLoS One
Volume 6, Issue 5, Pages e19527
Publisher
Public Library of Science (PLoS)
Online
2011-05-13
DOI
10.1371/journal.pone.0019527

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