NCI60 Cancer Cell Line Panel Data and RNAi Analysis Help Identify EAF2 as a Modulator of Simvastatin and Lovastatin Response in HCT-116 Cells

Bioinformatic analyses identifies novel protein-coding pharmacogenomic markers associated with paclitaxel sensitivity in NCI60 cancer cell lines

(2011) Lawson Eng et al.   BMC Medical Genomics

Lovastatin induces apoptosis of ovarian cancer cells and synergizes with doxorubicin: potential therapeutic relevance

(2010) Anna Martirosyan et al.   BMC CANCER

A Whole-Genome SNP Association Study of NCI60 Cell Line Panel Indicates a Role of Ca2+ Signaling in Selenium Resistance

(2010) Sevtap Savas et al.   PLoS One

Statins inhibit the growth of variant human embryonic stem cells and cancer cellsin vitrobut not normal human embryonic stem cells

(2009) K Gauthaman et al.   BRITISH JOURNAL OF PHARMACOLOGY

Statins, stem cells, and cancer

(2009) Kalamegam Gauthaman et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Synthetic lethal RNAi screening identifies sensitizing targets for gemcitabine therapy in pancreatic cancer

(2009) David O Azorsa et al.   Journal of Translational Medicine

Statins Inhibit Proliferation and Induce Apoptosis in Barrett's Esophageal Adenocarcinoma Cells

(2008) Olorunseun O. Ogunwobi et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

HMG-CoA reductase inhibitor simvastatin overcomes bortezomib-induced apoptosis resistance by disrupting a geranylgeranyl pyrophosphate-dependent survival pathway

(2008) Dominik Fuchs et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Possibility of Simvastatin as a Chemotherapeutic Agent for All-trans Retinoic Acid-Resistant Promyelocytic Leukemia

(2008) Naoki Tomiyama et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Discovery of genetic profiles impacting response to chemotherapy: application to gemcitabine

(2008) Hamdi Jarjanazi et al.   HUMAN MUTATION