Multiple Wnt/ß-Catenin Responsive Enhancers Align with the MYC Promoter through Long-Range Chromatin Loops
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Title
Multiple Wnt/ß-Catenin Responsive Enhancers Align with the MYC Promoter through Long-Range Chromatin Loops
Authors
Keywords
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Journal
PLoS One
Volume 6, Issue 4, Pages e18966
Publisher
Public Library of Science (PLoS)
Online
2011-04-21
DOI
10.1371/journal.pone.0018966
References
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Note: Only part of the references are listed.- Upregulation of c-MYC in cis through a Large Chromatin Loop Linked to a Cancer Risk-Associated Single-Nucleotide Polymorphism in Colorectal Cancer Cells
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- Mediator and cohesin connect gene expression and chromatin architecture
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- The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation
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- Identification of β-catenin binding regions in colon cancer cells using ChIP-Seq
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- Long-range enhancers on 8q24 regulate c-Myc
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- 8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC
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- Enhancers: The abundance and function of regulatory sequences beyond promoters
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- The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer
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- The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling
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- ENCODE whole-genome data in the UCSC Genome Browser
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- A -catenin/TCF-coordinated chromatin loop at MYC integrates 5' and 3' Wnt responsive enhancers
- (2009) G. S. Yochum et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional Enhancers at the Gene-Poor 8q24 Cancer-Linked Locus
- (2009) Li Jia et al. PLoS Genetics
- Myc's broad reach
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- A Genome-Wide Screen for -Catenin Binding Sites Identifies a Downstream Enhancer Element That Controls c-Myc Gene Expression
- (2008) G. S. Yochum et al. MOLECULAR AND CELLULAR BIOLOGY
- Genome-Wide Pattern of TCF7L2/TCF4 Chromatin Occupancy in Colorectal Cancer Cells
- (2008) P. Hatzis et al. MOLECULAR AND CELLULAR BIOLOGY
- Long-range chromosomal interactions and gene regulation
- (2008) Adriana Miele et al. Molecular BioSystems
- Modelling Myc inhibition as a cancer therapy
- (2008) Laura Soucek et al. NATURE
- Cohesin mediates transcriptional insulation by CCCTC-binding factor
- (2008) Kerstin S. Wendt et al. NATURE
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