ENPP1 Affects Insulin Action and Secretion: Evidences from In Vitro Studies

TheENPP1Q121 Variant Predicts Major Cardiovascular Events in High-Risk Individuals

(2011) Simonetta Bacci et al.   DIABETES

Prep1 Controls Insulin Glucoregulatory Function in Liver by Transcriptional Targeting of SHP1 Tyrosine Phosphatase

(2010) F. Oriente et al.   DIABETES

TRIB3 R84 variant affects glucose homeostasis by altering the interplay between insulin sensitivity and secretion

(2010) S. Prudente et al.   DIABETOLOGIA

Glucosamine-induced endoplasmic reticulum stress affects GLUT4 expression via activating transcription factor 6 in rat and human skeletal muscle cells

(2010) G. A. Raciti et al.   DIABETOLOGIA

The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse β cells

(2010) Chong Wee Liew et al.   JOURNAL OF CLINICAL INVESTIGATION

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

(2010) Benjamin F Voight et al.   NATURE GENETICS

Type 2 Diabetes Susceptibility Gene Expression in Normal or Diabetic Sorted Human Alpha and Beta Cells: Correlations with Age or BMI of Islet Donors

(2010) Clare L. Kirkpatrick et al.   PLoS One

ENPP1 Q121 Variant, Increased Pulse Pressure and Reduced Insulin Signaling, and Nitric Oxide Synthase Activity in Endothelial Cells

(2009) Simonetta Bacci et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Evidence that inhibition of insulin receptor signaling activity by PC-1/ENPP1 is dependent on its enzyme activity

(2009) Chen-Ni Chin et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Suppression of PC-1/ENPP-1 expression improves insulin sensitivity in vitro and in vivo

(2009) Heather H. Zhou et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Insulin signaling regulating genes: effect on T2DM and cardiovascular risk

(2009) Sabrina Prudente et al.   Nature Reviews Endocrinology

TRIB3 R84 Variant Is Associated With Impaired Insulin-Mediated Nitric Oxide Production in Human Endothelial Cells

(2008) Francesco Andreozzi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of the ENPP1 K121Q Polymorphism in Glucose Homeostasis

(2008) R. Baratta et al.   DIABETES

Haplotype Structure of the ENPP1 Gene and Nominal Association of the K121Q Missense Single Nucleotide Polymorphism With Glycemic Traits in the Framingham Heart Study

(2008) E. S. Stolerman et al.   DIABETES

The Role of Membrane Glycoprotein Plasma Cell Antigen 1/Ectonucleotide Pyrophosphatase Phosphodiesterase 1 in the Pathogenesis of Insulin Resistance and Related Abnormalities

(2008) Ira D. Goldfine et al.   ENDOCRINE REVIEWS

TheTRIB3Q84R Polymorphism and Risk of Early-Onset Type 2 Diabetes

(2008) Sabrina Prudente et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The role of HSP70 on ENPP1 expression and insulin-receptor activation

(2008) Antonella Marucci et al.   JOURNAL OF MOLECULAR MEDICINE-JMM