A Better Anti-Diabetic Recombinant Human Fibroblast Growth Factor 21 (rhFGF21) Modified with Polyethylene Glycol

Role of FGF19 induced FGFR4 activation in the regulation of glucose homeostasis

(2016) Xinle Wu et al.   Aging-US

High-level expression and purification of soluble recombinant FGF21 protein by SUMO fusion in Escherichia coli

(2010) Huiyan Wang et al.   BMC BIOTECHNOLOGY

Poly(ethylene glycol) modification enhances penetration of fibroblast growth factor 2 to injured spinal cord tissue from an intrathecal delivery system

(2010) Catherine E. Kang et al.   JOURNAL OF CONTROLLED RELEASE

FGF-21 enhances islet engraftment in mouse syngeneic islet transplantation model

(2010) Taeko Uonaga et al.   Islets

PEG conjugates in clinical development or use as anticancer agents: An overview

(2009) Gianfranco Pasut et al.   ADVANCED DRUG DELIVERY REVIEWS

Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models—association with liver and adipose tissue effects

(2009) Jing Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Different roles of N- and C- termini in the functional activity of FGF21

(2009) Radmila Micanovic et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The FGF family: biology, pathophysiology and therapy

(2009) Andrew Beenken et al.   NATURE REVIEWS DRUG DISCOVERY

Increasing Solubility of Proteins and Peptides by Site-Specific Modification with Betaine

(2008) Junpeng Xiao et al.   BIOCONJUGATE CHEMISTRY

The Impact of PEGylation on Biological Therapies

(2008) Francesco M Veronese et al.   BIODRUGS

Serum FGF21 Levels Are Increased in Obesity and Are Independently Associated With the Metabolic Syndrome in Humans

(2008) X. Zhang et al.   DIABETES

Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice

(2008) J. Xu et al.   DIABETES

Fibroblast Growth Factor 21 Corrects Obesity in Mice

(2008) Tamer Coskun et al.   ENDOCRINOLOGY

FGF21 N- and C-termini play different roles in receptor interaction and activation

(2008) Junming Yie et al.   FEBS LETTERS

FGF21 is an Akt-regulated myokine

(2008) Yasuhiro Izumiya et al.   FEBS LETTERS

Physiological Regulation and Disorders of Phosphate Metabolism -Pivotal Role of Fibroblast Growth Factor 23-

(2008) Seiji Fukumoto   INTERNAL MEDICINE

βKlotho Is Required for Fibroblast Growth Factor (FGF) 21 Signaling through FGF Receptor (FGFR) 1c and FGFR3c

(2008) Masashi Suzuki et al.   MOLECULAR ENDOCRINOLOGY

FGF-21/FGF-21 receptor interaction and activation is determined by βKlotho

(2007) Alexei Kharitonenkov et al.   JOURNAL OF CELLULAR PHYSIOLOGY