Role of IL-1 Beta in the Development of Human TH17 Cells: Lesson from NLPR3 Mutated Patients

Cutting Edge: IL-1 Controls the IL-23 Response Induced by Gliadin, the Etiologic Agent in Celiac Disease

(2014) K. M. Harris et al.   JOURNAL OF IMMUNOLOGY

Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans

(2010) Shinobu Saijo et al.   IMMUNITY

Interleukin-9 as a T helper type 17 cytokine

(2010) Elizabeth C. Nowak et al.   IMMUNOLOGY

Follow-Up and Quality of Life of Patients with Cryopyrin-Associated Periodic Syndromes Treated with Anakinra

(2010) Loredana Lepore et al.   JOURNAL OF PEDIATRICS

Successful Treatment of Castleman's Disease with Interleukin-1 Receptor Antagonist (Anakinra)

(2010) H. El-Osta et al.   MOLECULAR CANCER THERAPEUTICS

Generation of pathogenic TH17 cells in the absence of TGF-β signalling

(2010) Kamran Ghoreschi et al.   NATURE

Altered redox state of monocytes from cryopyrin-associated periodic syndromes causes accelerated IL-1  secretion

(2010) S. Tassi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

(2010) K. Nistala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development, regulation and functional capacities of Th17 cells

(2010) Keiji Hirota et al.   Seminars in Immunopathology

Subtype-specific peripheral blood gene expression profiles in recent-onset juvenile idiopathic arthritis

(2009) Michael G. Barnes et al.   ARTHRITIS AND RHEUMATISM

The myeloid-related proteins 8 and 14 complex, a novel ligand of toll-like receptor 4, and interleukin-1β form a positive feedback mechanism in systemic-onset juvenile idiopathic arthritis

(2009) Michael Frosch et al.   ARTHRITIS AND RHEUMATISM

Inflammasome-Mediated Disease Animal Models Reveal Roles for Innate but Not Adaptive Immunity

(2009) Susannah D. Brydges et al.   IMMUNITY

A Mutation in the Nlrp3 Gene Causing Inflammasome Hyperactivation Potentiates Th17 Cell-Dominant Immune Responses

(2009) Guangxun Meng et al.   IMMUNITY

Critical Regulation of Early Th17 Cell Differentiation by Interleukin-1 Signaling

(2009) Yeonseok Chung et al.   IMMUNITY

Regulation of interleukin-12/interleukin-23 production and the T-helper 17 response in humans

(2009) Lyudmila Lyakh et al.   IMMUNOLOGICAL REVIEWS

Targeting the Pathogenic Role of Interleukin 1β in the Progression of Smoldering/Indolent Myeloma to Active Disease

(2009) Charles A. Dinarello   MAYO CLINIC PROCEEDINGS

Interleukin-17 and Type 17 Helper T Cells

(2009) Pierre Miossec et al.   NEW ENGLAND JOURNAL OF MEDICINE

IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation

(2009) S. Z. Ben-Sasson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The pattern of response to anti–interleukin-1 treatment distinguishes two subsets of patients with systemic-onset juvenile idiopathic arthritis

(2008) Marco Gattorno et al.   ARTHRITIS AND RHEUMATISM

Differential regulation of interleukin 12 and interleukin 23 production in human dendritic cells

(2008) Franca Gerosa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

(2008) Marc Veldhoen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled, withdrawal phase III trial

(2008) Shumpei Yokota et al.   LANCET

Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

(2008) Joshua D. Milner et al.   NATURE

Differentiation of human TH-17 cells does require TGF-β!

(2008) Anne O'Garra et al.   NATURE IMMUNOLOGY