Porcine Sialoadhesin (CD169/Siglec-1) Is an Endocytic Receptor that Allows Targeted Delivery of Toxins and Antigens to Macrophages

Fusion Proteins for Versatile Antigen Targeting to Cell Surface Receptors Reveal Differential Capacity to Prime Immune Responses

(2010) R. Kratzer et al.   JOURNAL OF IMMUNOLOGY

CD169+ macrophages present lipid antigens to mediate early activation of iNKT cells in lymph nodes

(2010) Patricia Barral et al.   NATURE IMMUNOLOGY

A Screen for Endocytic Motifs

(2010) Patrycja Kozik et al.   TRAFFIC

The M/GP5 Glycoprotein Complex of Porcine Reproductive and Respiratory Syndrome Virus Binds the Sialoadhesin Receptor in a Sialic Acid-Dependent Manner

(2010) Wander Van Breedam et al.   PLoS Pathogens

PEGylation of Anti-Sialoadhesin Monoclonal Antibodies Enhances Their Inhibitory Potencies without Impairing Endocytosis in Mouse Peritoneal Macrophages

(2009) Julie Ducreux et al.   BIOCONJUGATE CHEMISTRY

Sialoadhesin-Positive Macrophages Bind Regulatory T Cells, Negatively Controlling Their Expansion and Autoimmune Disease Progression

(2009) Chuan Wu et al.   JOURNAL OF IMMUNOLOGY

Effective collaboration between marginal metallophilic macrophages and CD8+ dendritic cells in the generation of cytotoxic T cells

(2009) R. Backer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Siglecs as targets for therapy in immune-cell-mediated disease

(2009) Mary K. O’Reilly et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Sialoadhesin and CD163 join forces during entry of the porcine reproductive and respiratory syndrome virus

(2008) H. Van Gorp et al.   JOURNAL OF GENERAL VIROLOGY

Surface-expressed viral proteins in feline infectious peritonitis virus-infected monocytes are internalized through a clathrin- and caveolae-independent pathway

(2008) H. L. Dewerchin et al.   JOURNAL OF GENERAL VIROLOGY

Sialoadhesin Expressed on IFN-Induced Monocytes Binds HIV-1 and Enhances Infectivity

(2008) Hans Rempel et al.   PLoS One

Targeting to porcine sialoadhesin receptor receptor improves antigen presentation to T cells

(2008) Concepción Revilla et al.   VETERINARY RESEARCH