2-Hydroxyglutarate Production, but Not Dominant Negative Function, Is Conferred by Glioma-Derived NADP+-Dependent Isocitrate Dehydrogenase Mutations
Published 2011 View Full Article
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Title
2-Hydroxyglutarate Production, but Not Dominant Negative Function, Is Conferred by Glioma-Derived NADP+-Dependent Isocitrate Dehydrogenase Mutations
Authors
Keywords
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Journal
PLoS One
Volume 6, Issue 2, Pages e16812
Publisher
Public Library of Science (PLoS)
Online
2011-02-05
DOI
10.1371/journal.pone.0016812
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Related references
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- Mutant Metabolic Enzymes Are at the Origin of Gliomas
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- Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers
- (2009) Mi Ran Kang et al. INTERNATIONAL JOURNAL OF CANCER
- Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
- (2009) Lenny Dang et al. NATURE
- IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas
- (2009) Koichi Ichimura et al. NEURO-ONCOLOGY
- Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome
- (2009) Elaine R. Mardis et al. NEW ENGLAND JOURNAL OF MEDICINE
- IDH1andIDH2Mutations in Gliomas
- (2009) Hai Yan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Glioma-Derived Mutations in IDH1 Dominantly Inhibit IDH1 Catalytic Activity and Induce HIF-1
- (2009) S. Zhao et al. SCIENCE
- An Integrated Genomic Analysis of Human Glioblastoma Multiforme
- (2008) D. W. Parsons et al. SCIENCE
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