Improved Innate and Adaptive Immunostimulation by Genetically Modified HIV-1 Protein Expressing NYVAC Vectors

Attenuated poxvirus vectors MVA and NYVAC as promising vaccine cadidates against HIV/AIDS

(2014) Mariano Esteban   Human vaccines & immunotherapeutics

Insertion of Vaccinia Virus C7L Host Range Gene into NYVAC-B Genome Potentiates Immune Responses against HIV-1 Antigens

(2010) José Luis Nájera et al.   PLoS One

Dendritic cells require a systemic type I interferon response to mature and induce CD4+Th1 immunity with poly IC as adjuvant

(2009) M. Paula Longhi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ORFeome approach to the clonal, HLA allele-specific CD4 T-cell response to a complex pathogen in humans

(2009) Lichen Jing et al.   JOURNAL OF IMMUNOLOGICAL METHODS

The Interferon System and Vaccinia Virus Evasion Mechanisms

(2009) Beatriz Perdiguero et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Comparison of Human and Rhesus Macaque T-Cell Responses Elicited by Boosting with NYVAC Encoding Human Immunodeficiency Virus Type 1 Clade C Immunogens

(2009) P. Mooij et al.   JOURNAL OF VIROLOGY

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antigen storage compartments in mature dendritic cells facilitate prolonged cytotoxic T lymphocyte cross-priming capacity

(2009) N. van Montfoort et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Poxvirus Vectors MVA and NYVAC as Gene Delivery Systems for Vaccination Against Infectious Diseases and Cancer

(2008) Carmen Gomez et al.   CURRENT GENE THERAPY

Vaccinia virus-specific CD8+ T-cell responses target a group of epitopes without a strong immunodominance hierarchy in humans

(2008) Masanori Terajima et al.   HUMAN IMMUNOLOGY

A Modular Analysis Framework for Blood Genomics Studies: Application to Systemic Lupus Erythematosus

(2008) Damien Chaussabel et al.   IMMUNITY

Cancer Immunotherapy by Dendritic Cells

(2008) Cornelis J.M. Melief   IMMUNITY

An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responses

(2008) Alexandre Harari et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development?

(2008) Rafick-Pierre Sekaly   JOURNAL OF EXPERIMENTAL MEDICINE

Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses

(2008) Denis Gaucher et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Differential CD4+ versus CD8+ T-Cell Responses Elicited by Different Poxvirus-Based Human Immunodeficiency Virus Type 1 Vaccine Candidates Provide Comparable Efficacies in Primates

(2008) P. Mooij et al.   JOURNAL OF VIROLOGY

EV01: A phase I trial in healthy HIV negative volunteers to evaluate a clade C HIV vaccine, NYVAC-C undertaken by the EuroVacc Consortium

(2008) Pierre-Alexandre Bart et al.   VACCINE

EV02: A Phase I trial to compare the safety and immunogenicity of HIV DNA-C prime-NYVAC-C boost to NYVAC-C alone

(2008) Sheena McCormack et al.   VACCINE