Structure-Function Study of Mammalian Munc18-1 and C. elegans UNC-18 Implicates Domain 3b in the Regulation of Exocytosis

Binding of Munc18-1 to Synaptobrevin and to the SNARE Four-Helix Bundle

(2010) Yi Xu et al.   BIOCHEMISTRY

SNARE bundle and syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion

(2010) Jingshi Shen et al.   JOURNAL OF CELL BIOLOGY

Mso1p Regulates Membrane Fusion through Interactions with the Putative N-Peptide–binding Area in Sec1p Domain 1

(2010) Marion Weber et al.   MOLECULAR BIOLOGY OF THE CELL

A Guide to Simple and Informative Binding Assays

(2010) Thomas D. Pollard   MOLECULAR BIOLOGY OF THE CELL

Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE-Sec1/Munc18 membrane fusion complex

(2010) S. S. Rathore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Functions of Munc18-1 in Regulated Exocytosis

(2009) Robert D. Burgoyne et al.   Annals of the New York Academy of Sciences

Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming

(2009) Ferenc Deák et al.   JOURNAL OF CELL BIOLOGY

Rescue of Munc18-1 and -2 Double Knockdown Reveals the Essential Functions of Interaction between Munc18 and Closed Syntaxin in PC12 Cells

(2009) Liping Han et al.   MOLECULAR BIOLOGY OF THE CELL

Membrane Fusion: Grappling with SNARE and SM Proteins

(2009) T. C. Sudhof et al.   SCIENCE

A gain-of-function mutant of Munc18-1 stimulates secretory granule recruitment and exocytosis and reveals a direct interaction of Munc18-1 with Rab3

(2008) Margaret E. Graham et al.   BIOCHEMICAL JOURNAL

Binding of UNC-18 to the N-terminus of syntaxin is essential for neurotransmission inCaenorhabditis elegans

(2008) James R. Johnson et al.   BIOCHEMICAL JOURNAL

Munc18a controls SNARE assembly through its interaction with the syntaxin N-peptide

(2008) Pawel Burkhardt et al.   EMBO JOURNAL

A Random Mutagenesis Approach to Isolate Dominant-Negative Yeast sec1 Mutants Reveals a Functional Role for Domain 3a in Yeast and Mammalian Sec1/Munc18 Proteins

(2008) A. Boyd et al.   GENETICS

UNC-18 Promotes Both the Anterograde Trafficking and Synaptic Function of Syntaxin

(2008) Jason M. McEwen et al.   MOLECULAR BIOLOGY OF THE CELL

UNC-18 Modulates Ethanol Sensitivity in Caenorhabditis elegans

(2008) Margaret E. Graham et al.   MOLECULAR BIOLOGY OF THE CELL

Munc-18-1 Regulates the Initial Release Rate of Exocytosis

(2007) Jeff W. Barclay   BIOPHYSICAL JOURNAL