Novel HTS Strategy Identifies TRAIL-Sensitizing Compounds Acting Specifically Through the Caspase-8 Apoptotic Axis

TRAIL induces endocytosis of its death receptors in MDA-MB-231 breast cancer cells

(2010) Yaqin Zhang et al.   CANCER BIOLOGY & THERAPY

Genistein sensitizes human hepatocellular carcinoma cells to TRAIL-mediated apoptosis by enhancing Bid cleavage

(2009) Cheng-Yun Jin et al.   ANTI-CANCER DRUGS

Critical Role for Caspase-8 in Epidermal Growth Factor Signaling

(2009) D. Finlay et al.   CANCER RESEARCH

Induction of death receptor ligand-mediated apoptosis in epithelial ovarian carcinoma: The search for sensitizing agents

(2009) Katherine Marie Moxley et al.   GYNECOLOGIC ONCOLOGY

TRAILing death in cancer

(2009) Gregory Mellier et al.   MOLECULAR ASPECTS OF MEDICINE

TRAIL-induced apoptosis of hepatocellular carcinoma cells isaugmented by targeted therapies

(2009) Bruno Christian Koehler et al.   WORLD JOURNAL OF GASTROENTEROLOGY

A cell-based high-throughput screen to identify synergistic TRAIL sensitizers

(2008) Nancy Lynn Booth et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Directing cancer cells to self-destruct with pro-apoptotic receptor agonists

(2008) Avi Ashkenazi   NATURE REVIEWS DRUG DISCOVERY