Common Polymorphisms in MTNR1B, G6PC2 and GCK Are Associated with Increased Fasting Plasma Glucose and Impaired Beta-Cell Function in Chinese Subjects

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

(2010) Josée Dupuis et al.   NATURE GENETICS

Common Genetic Determinants of Glucose Homeostasis in Healthy Children

(2009) Clara Kelliny et al.   DIABETES

G-allele of Intronic rs10830963 in MTNR1B Confers Increased Risk of Impaired Fasting Glycemia and Type 2 Diabetes Through an Impaired Glucose-Stimulated Insulin Release: Studies Involving 19,605 Europeans

(2009) T. Sparso et al.   DIABETES

Association of GCKR rs780094, alone or in combination with GCK rs1799884, with type 2 diabetes and related traits in a Han Chinese population

(2009) Q. Qi et al.   DIABETOLOGIA

A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads

(2009) C. S. Rose et al.   DIABETOLOGIA

Common variants at the GCK, GCKR, G6PC2–ABCB11 and MTNR1B loci are associated with fasting glucose in two Asian populations

(2009) F. Takeuchi et al.   DIABETOLOGIA

Common genetic variation in the melatonin receptor 1B gene (MTNR1B) is associated with decreased early-phase insulin response

(2009) C. Langenberg et al.   DIABETOLOGIA

A common variant in MTNR1B, encoding melatonin receptor 1B, is associated with type 2 diabetes and fasting plasma glucose in Han Chinese individuals

(2009) T. Rönn et al.   DIABETOLOGIA

Loss of melatonin signalling and its impact on circadian rhythms in mouse organs regulating blood glucose

(2009) Eckhard Mühlbauer et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Interaction Effect of Genetic Polymorphisms in Glucokinase (GCK) and Glucokinase Regulatory Protein (GCKR) on Metabolic Traits in Healthy Chinese Adults and Adolescents

(2008) C. H.T. Tam et al.   DIABETES

Implication of Genetic Variants Near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in Type 2 Diabetes and Obesity in 6,719 Asians

(2008) M. C.Y. Ng et al.   DIABETES

A genetic variant of G6PC2 is associated with type 2 diabetes and fasting plasma glucose level in the Chinese population

(2008) C. Hu et al.   DIABETOLOGIA

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

(2008) Valeriya Lyssenko et al.   NATURE GENETICS

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

(2008) Eleftheria Zeggini et al.   NATURE GENETICS

Variants in MTNR1B influence fasting glucose levels

(2008) Inga Prokopenko et al.   NATURE GENETICS

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

(2008) Nabila Bouatia-Naji et al.   NATURE GENETICS

A Polymorphism Within the G6PC2 Gene Is Associated with Fasting Plasma Glucose Levels

(2008) N. Bouatia-Naji et al.   SCIENCE

O-GlcNAc modification of transcription factors, glucose sensing and glucotoxicity

(2008) Tarik Issad et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM