The G215R Mutation in the Cl−/H+-Antiporter ClC-7 Found in ADO II Osteopetrosis Does Not Abolish Function but Causes a Severe Trafficking Defect

The Late Endosomal ClC-6 Mediates Proton/Chloride Countertransport in Heterologous Plasma Membrane Expression

(2010) Ioana Neagoe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysosomal Pathology and Osteopetrosis upon Loss of H+-Driven Lysosomal Cl- Accumulation

(2010) S. Weinert et al.   SCIENCE

CLC-7: A potential therapeutic target for the treatment of osteoporosis and neurodegeneration

(2009) Qingxiao Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lysosomal degradation of endocytosed proteins depends on the chloride transport protein ClC-7

(2009) Lena Wartosch et al.   FASEB JOURNAL

Chloride channels as drug targets

(2009) Alan S. Verkman et al.   NATURE REVIEWS DRUG DISCOVERY

Characteristics of ClC7 Cl− channels and their inhibition in mutant (G215R) associated with autosomal dominant osteopetrosis type II in native osteoclasts and hClcn7 gene-expressing cells

(2009) Hiroshi Kajiya et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Characterization of acid flux in osteoclasts from patients harboring a G215R mutation in ClC-7

(2008) Kim Henriksen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ion Transporters Involved in Acidification of the Resorption Lacuna in Osteoclasts

(2008) Kim Henriksen et al.   CALCIFIED TISSUE INTERNATIONAL

CLC Chloride Channels and Transporters: From Genes to Protein Structure, Pathology and Physiology

(2008) Thomas J. Jentsch   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Role of the Vesicular Chloride Transporter ClC-3 in Neuroendocrine Tissue

(2008) T. Maritzen et al.   JOURNAL OF NEUROSCIENCE

SSM-based electrophysiology

(2008) Patrick Schulz et al.   METHODS

The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes

(2008) Austin R. Graves et al.   NATURE

Physiological roles of CLC Cl−/H+ exchangers in renal proximal tubules

(2008) Vanessa Plans et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Overexpression of CLC-3 in HEK293T cells yields novel currents that are pH dependent

(2007) James J. Matsuda et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY