Potent New Small-Molecule Inhibitor of Botulinum Neurotoxin Serotype A Endopeptidase Developed by Synthesis-Based Computer-Aided Molecular Design

Identification and Biochemical Characterization of Small-Molecule Inhibitors of Clostridium botulinum Neurotoxin Serotype A

(2009) V. Roxas-Duncan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Botulinum neurotoxin serotype A inhibitors: Small-molecule mercaptoacetamide analogs

(2009) Scott T. Moe et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Pharmacophore-guided lead optimization: The rational design of a non-zinc coordinating, sub-micromolar inhibitor of the botulinum neurotoxin serotype a metalloprotease

(2009) J.C. Burnett et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Evaluating the Performance of the ff99SB Force Field Based on NMR Scalar Coupling Data

(2009) Lauren Wickstrom et al.   BIOPHYSICAL JOURNAL

U.S. Army Botulinum Neurotoxin (BoNT) Medical Therapeutics Research Program: past accomplishments and future directions

(2009) Joseph C. Larsen   DRUG DEVELOPMENT RESEARCH

Structure of HI-6•Sarin-Acetylcholinesterase Determined by X-Ray Crystallography and Molecular Dynamics Simulation: Reactivator Mechanism and Design

(2009) Fredrik Ekström et al.   PLoS One

Tandem fluorescent proteins as enhanced FRET-based substrates for botulinum neurotoxin activity

(2009) Melissa Pires-Alves et al.   TOXICON

Catalytic Features of the Botulinum Neurotoxin A Light Chain Revealed by High Resolution Structure of an Inhibitory Peptide Complex†‡

(2008) Nicholas R. Silvaggi et al.   BIOCHEMISTRY

Rhodanine Derivatives as Selective Protease Inhibitors Against Bacterial Toxins

(2008) Sherida L. Johnson et al.   Chemical Biology & Drug Design

A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has a Very Different Conformation than SNAP-25 Substrate

(2008) Jorge E. Zuniga et al.   STRUCTURE