Systematic Analysis of Immune Infiltrates in High-Grade Serous Ovarian Cancer Reveals CD20, FoxP3 and TIA-1 as Positive Prognostic Factors
Published 2009 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Systematic Analysis of Immune Infiltrates in High-Grade Serous Ovarian Cancer Reveals CD20, FoxP3 and TIA-1 as Positive Prognostic Factors
Authors
Keywords
T cells, Cytotoxic T cells, Major histocompatibility complex, Regulatory T cells, Macrophages, Lymphocytes, Histology, Prognosis
Journal
PLoS One
Volume 4, Issue 7, Pages e6412
Publisher
Public Library of Science (PLoS)
Online
2009-07-29
DOI
10.1371/journal.pone.0006412
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- FOXP3 Defines Regulatory T Cells in Human Tumor and Autoimmune Disease
- (2009) I. Kryczek et al. CANCER RESEARCH
- Interleukin 2-mediated Conversion of Ovarian Cancer-associated CD4+ Regulatory T Cells Into Proinflammatory Interleukin 17-producing Helper T Cells
- (2009) Lucie Leveque et al. JOURNAL OF IMMUNOTHERAPY
- Identification of IL-17-producing FOXP3+ regulatory T cells in humans
- (2009) K. S. Voo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines
- (2008) M. A. Morse et al. BLOOD
- FOXP3 expression accurately defines the population of intratumoral regulatory T cells that selectively accumulate in metastatic melanoma lesions
- (2008) M. Ahmadzadeh et al. BLOOD
- CD49d provides access to "untouched" human Foxp3+ Treg free of contaminating effector cells
- (2008) M. Kleinewietfeld et al. BLOOD
- Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells
- (2008) H. J. P. M. Koenen et al. BLOOD
- Molecular profiling of classical Hodgkin lymphoma tissues uncovers variations in the tumor microenvironment and correlations with EBV infection and outcome
- (2008) B. Chetaille et al. BLOOD
- Prognostic significance of tumor-infiltrating T-lymphocytes in primary and metastatic lesions of advanced stage ovarian cancer
- (2008) Ninke Leffers et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- The Regulatory T Cell-Associated Transcription Factor FoxP3 Is Expressed by Tumor Cells
- (2008) L. M. Ebert et al. CANCER RESEARCH
- Prevention of Both Direct and Cross-Priming of Antitumor CD8+ T-Cell Responses following Overproduction of Prostaglandin E2 by Tumor Cells In vivo
- (2008) M. Ahmadi et al. CANCER RESEARCH
- The Humoral Immune System Has a Key Prognostic Impact in Node-Negative Breast Cancer
- (2008) M. Schmidt et al. CANCER RESEARCH
- Novel Molecular Subtypes of Serous and Endometrioid Ovarian Cancer Linked to Clinical Outcome
- (2008) R. W. Tothill et al. CLINICAL CANCER RESEARCH
- Increased HLA-DMB Expression in the Tumor Epithelium Is Associated with Increased CTL Infiltration and Improved Prognosis in Advanced-Stage Serous Ovarian Cancer
- (2008) M. J. Callahan et al. CLINICAL CANCER RESEARCH
- HLA Class I Antigen Processing Machinery Component Expression and Intratumoral T-Cell Infiltrate as Independent Prognostic Markers in Ovarian Carcinoma
- (2008) L. Y. Han et al. CLINICAL CANCER RESEARCH
- Prognostic Effect of Epithelial and Stromal Lymphocyte Infiltration in Non-Small Cell Lung Cancer
- (2008) K. I. Al-Shibli et al. CLINICAL CANCER RESEARCH
- Regulatory T cells in health and disease
- (2008) Ciriaco A. Piccirillo CYTOKINE
- Is FOXP3 a bona fide marker for human regulatory T cells?
- (2008) Maria-Grazia Roncarolo et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- IL-15 acts as a potent inducer of CD4+CD25hi cells expressing FOXP3
- (2008) Hiromi Imamichi et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Survival of ovarian cancer patients overexpressing the tumour antigen p53 is diminished in case of MHC class I down-regulation
- (2008) Ninke Leffers et al. GYNECOLOGIC ONCOLOGY
- Intratumoral T cells, tumor-associated macrophages, and regulatory T cells: Association with p53 mutations, circulating tumor DNA and survival in women with ovarian cancer
- (2008) Chirag A. Shah et al. GYNECOLOGIC ONCOLOGY
- Impact of the tumor microenvironment on prognosis in follicular lymphoma is dependent on specific treatment protocols
- (2008) D. de Jong et al. HAEMATOLOGICA
- The impact of T-cell immunity on ovarian cancer outcomes
- (2008) Brad H. Nelson IMMUNOLOGICAL REVIEWS
- B-lymphocyte contributions to human autoimmune disease
- (2008) Koichi Yanaba et al. IMMUNOLOGICAL REVIEWS
- Tumor-Infiltrating FOXP3+ T Regulatory Cells Show Strong Prognostic Significance in Colorectal Cancer
- (2008) Paul Salama et al. JOURNAL OF CLINICAL ONCOLOGY
- FOXP3 immunohistochemistry on formalin-fixed paraffin-embedded tissue: poor correlation between different antibodies
- (2008) Y L Woo et al. JOURNAL OF CLINICAL PATHOLOGY
- Partial Reduction of Human FOXP3+ CD4 T Cells In Vivo After CD25-directed Recombinant Immunotoxin Administration
- (2008) Daniel J. Powell et al. JOURNAL OF IMMUNOTHERAPY
- Transient T cell depletion causes regression of melanoma metastases
- (2008) Mary Rasku et al. Journal of Translational Medicine
- Foxp3 expression in human cancer cells
- (2008) Vaios Karanikas et al. Journal of Translational Medicine
- Intraepithelial T cells and prognosis in ovarian carcinoma: novel associations with stage, tumor type and BRCA1 loss
- (2008) Blaise Clarke et al. MODERN PATHOLOGY
- Classification using hierarchical clustering of tumor-infiltrating immune cells identifies poor prognostic ovarian cancers with high levels of COX expression
- (2008) Min Liu et al. MODERN PATHOLOGY
- Generation and regulation of human CD4+ IL-17-producing T cells in ovarian cancer
- (2008) Y. Miyahara et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Expression of CD68 in Non-Myeloid Cell Types
- (2008) E. Gottfried et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Coordination of Early Protective Immunity to Viral Infection by Regulatory T Cells
- (2008) J. M. Lund et al. SCIENCE
- Macrophage polarization in tumour progression
- (2008) Antonio Sica et al. SEMINARS IN CANCER BIOLOGY
- Ovarian Carcinoma Subtypes Are Different Diseases: Implications for Biomarker Studies
- (2008) Martin Köbel et al. PLOS MEDICINE
- A comparative study of the cellular immune response in patients with stage IB cervical squamous cell carcinoma. Low numbers of several immune cell subtypes are strongly associated with relapse of disease within 5 years
- (2007) Bettina S. Nedergaard et al. GYNECOLOGIC ONCOLOGY
- Prognostic significance of CD3+ tumor-infiltrating lymphocytes in ovarian carcinoma
- (2007) Markéta Tomšová et al. GYNECOLOGIC ONCOLOGY
- Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy
- (2007) Ronald J Buckanovich et al. NATURE MEDICINE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started