Monitoringin vitrothrombus formation with novel microfluidic devices

Thrombus Growth and Embolism on Tissue Factor-Bearing Collagen Surfaces Under Flow

(2012) Thomas V. Colace et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Microfluidic system for simultaneous optical measurement of platelet aggregation at multiple shear rates in whole blood

(2012) Melissa Li et al.   LAB ON A CHIP

Measurement of whole blood thrombus formation using parallel-plate flow chambers – a practical guide

(2012) Roger Van Kruchten et al.   PLATELETS

Well plate microfluidic system for investigation of dynamic platelet behavior under variable shear loads

(2011) Carolyn G. Conant et al.   BIOTECHNOLOGY AND BIOENGINEERING

In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology

(2011) Michelle Tsai et al.   JOURNAL OF CLINICAL INVESTIGATION

Flow chamber-based assays to measure thrombus formation in vitro: requirements for standardization

(2011) M. ROEST et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Collagen surfaces to measure thrombus formation under flow: possibilities for standardization

(2011) J. W. M. HEEMSKERK et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A microchip flow-chamber system for quantitative assessment of the platelet thrombus formation process

(2011) Kazuya Hosokawa et al.   MICROVASCULAR RESEARCH

Platelet aggregation monitoring with a newly developed quartz crystal microbalance system as an alternative to optical platelet aggregometry

(2010) Stefan Sinn et al.   ANALYST

Integrated system investigating shear-mediated platelet interactions with von Willebrand factor using microliters of whole blood

(2010) Bryan Lincoln et al.   ANALYTICAL BIOCHEMISTRY

A circular cross-section PDMS microfluidics system for replication of cardiovascular flow conditions

(2010) Lindsey K. Fiddes et al.   BIOMATERIALS

Shear-Mediated Platelet Adhesion Analysis in Less Than 100 μ L of Blood: Toward a POC Platelet Diagnostic

(2010) Nigel J Kent et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

P2Y12 or P2Y1 inhibitors reduce platelet deposition in a microfluidic model of thrombosis while apyrase lacks efficacy under flow conditions

(2010) S. F. Maloney et al.   Integrative Biology

Comparison of Platelet Function Tests in Predicting Clinical Outcome in Patients Undergoing Coronary Stent Implantation

(2010) Nicoline J. Breet   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Design Considerations for a Microfluidic Device to Quantify the Platelet Adhesion to Collagen at Physiological Shear Rates

(2009) Durga P. Sarvepalli et al.   ANNALS OF BIOMEDICAL ENGINEERING

Dynamics of platelet thrombus formation

(2009) S. P. JACKSON et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Integrated microfluidic chip for endothelial cells culture and analysis exposed to a pulsatile and oscillatory shear stress

(2009) Jianbo Shao et al.   LAB ON A CHIP

A novel multishear microdevice for studying cell mechanics

(2009) Lien Chau et al.   LAB ON A CHIP

Simple and rapid process for single cell micro-patterning

(2009) Ammar Azioune et al.   LAB ON A CHIP

A microfluidics device to monitor platelet aggregation dynamics in response to strain rate micro-gradients in flowing blood

(2009) Francisco Javier Tovar-Lopez et al.   LAB ON A CHIP

A shear gradient–dependent platelet aggregation mechanism drives thrombus formation

(2009) Warwick S Nesbitt et al.   NATURE MEDICINE

Interactions between Multiple Cell Types in Parallel Microfluidic Channels: Monitoring Platelet Adhesion to an Endothelium in the Presence of an Anti-Adhesion Drug

(2008) Chia-Jui Ku et al.   ANALYTICAL CHEMISTRY

Threshold Response of Initiation of Blood Coagulation by Tissue Factor in Patterned Microfluidic Capillaries Is Controlled by Shear Rate

(2008) Feng Shen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Determination of surface tissue factor thresholds that trigger coagulation at venous and arterial shear rates: amplification of 100 fM circulating tissue factor requires flow

(2008) U. M. Okorie et al.   BLOOD

Endothelial Cell Migration in Stable Gradients of Vascular Endothelial Growth Factor A and Fibroblast Growth Factor 2

(2008) Irmeli Barkefors et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple ways to switch platelet integrins on and off

(2008) J. M. E. M. COSEMANS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Microfluidic focal thrombosis model for measuring murine platelet deposition and stability: PAR4 signaling enhances shear-resistance of platelet aggregates

(2008) K. B. NEEVES et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Microfluidic device for label-free measurement of platelet activation

(2008) David W. Inglis et al.   LAB ON A CHIP

Microfluidic devices for studies of shear-dependent platelet adhesion

(2008) Edgar Gutierrez et al.   LAB ON A CHIP

A membrane-based microfluidic device for controlling the flux of platelet agonists into flowing blood

(2008) Keith B. Neeves et al.   LAB ON A CHIP

Endothelial cell polarization and chemotaxis in a microfluidic device

(2008) Amir Shamloo et al.   LAB ON A CHIP

Using microfluidics to understand the effect of spatial distribution of tissue factor on blood coagulation

(2008) Feng Shen et al.   THROMBOSIS RESEARCH