A megakaryocyte with no platelets: Anti-platelet antibodies, apoptosis, and platelet production

Quinine-induced thrombocytopenia: drug-dependent GPIb/IX antibodies inhibit megakaryocyte and proplatelet production in vitro

(2011) J. Perdomo et al.   BLOOD

Platelet production and platelet destruction: assessing mechanisms of treatment effect in immune thrombocytopenia

(2011) S. J. Barsam et al.   BLOOD

Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets

(2011) Emma C. Josefsson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Drug-induced thrombocytopenia: development of a novel NOD/SCID mouse model to evaluate clearance of circulating platelets by drug-dependent antibodies and the efficacy of IVIG

(2010) S. X. Liang et al.   BLOOD

Contributions of TRAIL-mediated megakaryocyte apoptosis to impaired megakaryocyte and platelet production in immune thrombocytopenia

(2010) L. Yang et al.   BLOOD

Restored platelet function after romiplostim treatment in a patient with immune thrombocytopenic purpura

(2010) Elizabeth E. Gardiner et al.   BRITISH JOURNAL OF HAEMATOLOGY

Platelet apoptosis by cold-induced glycoprotein Ibα clustering

(2010) D. E. VAN DER WAL et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

TNF receptor-associated factor 4 (TRAF4) is a novel binding partner of glycoprotein Ib and glycoprotein VI in human platelets

(2010) J. F. ARTHUR et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Biology and Chemistry of Thrombopoietic Agents

(2010) David J. Kuter   SEMINARS IN HEMATOLOGY

Apoptotic Processes in Megakaryocytes and Platelets

(2010) Michael J. White et al.   SEMINARS IN HEMATOLOGY

Megakaryocyte impairment by eptifibatide-induced antibodies causes prolonged thrombocytopenia

(2009) A. Greinacher et al.   BLOOD

International consensus report on the investigation and management of primary immune thrombocytopenia

(2009) D. Provan et al.   BLOOD

Treatment practices in adults with chronic immune thrombocytopenia – a European perspective

(2009) Francesco Rodeghiero et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Eptifibatide-induced thrombocytopenia and thrombosis in humans require FcγRIIa and the integrin β3 cytoplasmic domain

(2009) Cunji Gao et al.   JOURNAL OF CLINICAL INVESTIGATION

The glycoprotein Ibα-von Willebrand factor interaction induces platelet apoptosis

(2009) S. LI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Caspase activation is involved in early megakaryocyte differentiation but not in platelet production from megakaryocytes

(2009) Y Kozuma et al.   LEUKEMIA

A functional 14-3-3 -independent association of PI3-kinase with glycoprotein Ib , the major ligand-binding subunit of the platelet glycoprotein Ib-IX-V complex

(2008) F.-T. Mu et al.   BLOOD

Adhesive receptors, extracellular proteins and myosin IIA orchestrate proplatelet formation by human megakaryocytes

(2008) A. BALDUINI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia

(2008) Ian M Morison et al.   NATURE GENETICS