Genome Editing of Mouse Fibroblasts by Homologous Recombination for Sustained Secretion of PDGF-B and Augmentation of Wound Healing

Combination of HIF-1α gene transfection and HIF-1-activated bone marrow-derived angiogenic cell infusion improves burn wound healing in aged mice

(2013) J Du et al.   GENE THERAPY

Epidermal Stem Cells Manipulated by pDNA-VEGF165/CYD-PEI Nanoparticles Loaded Gelatin/β-TCP Matrix as a Therapeutic Agent and Gene Delivery Vehicle for Wound Healing

(2013) Li-Hua Peng et al.   MOLECULAR PHARMACEUTICS

Generation of an HIV Resistant T-cell Line by Targeted “Stacking” of Restriction Factors

(2013) Richard A Voit et al.   MOLECULAR THERAPY

TALEN-based Gene Correction for Epidermolysis Bullosa

(2013) Mark J Osborn et al.   MOLECULAR THERAPY

Effective healing of diabetic skin wounds by using nonviral gene therapy based on minicircle vascular endothelial growth factor DNA and a cationic dendrimer

(2012) Min J. Kwon et al.   JOURNAL OF GENE MEDICINE

Adipose-derived Stromal Cells Overexpressing Vascular Endothelial Growth Factor Accelerate Mouse Excisional Wound Healing

(2012) Allison Nauta et al.   MOLECULAR THERAPY

Combined Gene and Stem Cell Therapy for Cutaneous Wound Healing

(2011) Gerd G. Gauglitz et al.   MOLECULAR PHARMACEUTICS

Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy

(2011) Antonio Di Stasi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B

(2011) Amit C. Nathwani et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia

(2011) David L. Porter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

(2011) Tomas Cermak et al.   NUCLEIC ACIDS RESEARCH

Comparison of EGF with VEGF Non-Viral Gene Therapy for Cutaneous Wound Healing of Streptozotocin Diabetic Mice

(2011) Junghae Ko et al.   Diabetes & Metabolism Journal

Targeted gene addition to human mesenchymal stromal cells as a cell-based plasma-soluble protein delivery platform

(2010) Basma F. Benabdallah et al.   CYTOTHERAPY

Repeat-induced gene silencing of L1 transgenes is correlated with differential promoter methylation

(2010) James M. Rosser et al.   GENE

Pre-clinical evaluation of liposomal gene transfer to improve dermal and epidermal regeneration

(2010) L K Branski et al.   GENE THERAPY

The mechanisms underlying fibroblast apoptosis regulated by growth factors during wound healing

(2010) Yoshikiyo Akasaka et al.   JOURNAL OF PATHOLOGY

Safety and efficacy of patient specific intramuscular injection of HGF plasmid gene therapy on limb perfusion and wound healing in patients with ischemic lower extremity ulceration: Results of the HGF-0205 trial

(2010) Richard J. Powell et al.   JOURNAL OF VASCULAR SURGERY

Gene Correction by Homologous Recombination With Zinc Finger Nucleases in Primary Cells From a Mouse Model of a Generic Recessive Genetic Disease

(2010) Jon P Connelly et al.   MOLECULAR THERAPY

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

(2010) Marina Cavazzana-Calvo et al.   NATURE

Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease

(2010) Stefan Stein et al.   NATURE MEDICINE

Stem-Cell Gene Therapy for the Wiskott–Aldrich Syndrome

(2010) Kaan Boztug et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

(2009) Dirk Hockemeyer et al.   NATURE BIOTECHNOLOGY

Treatment of nonhealing diabetic foot ulcers with a platelet-derived growth factor gene-activated matrix (GAM501): Results of a Phase 1/2 trial

(2009) Gerit Mulder et al.   WOUND REPAIR AND REGENERATION

Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

(2008) Salima Hacein-Bey-Abina et al.   JOURNAL OF CLINICAL INVESTIGATION

Insulin-like growth factor-1 gene therapy and cell transplantation in diabetic wounds

(2008) Tobias Hirsch et al.   JOURNAL OF GENE MEDICINE

Comparison of Zinc Finger Nucleases for Use in Gene Targeting in Mammalian Cells

(2008) Shondra M Pruett-Miller et al.   MOLECULAR THERAPY

Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis

(2008) Albert M. Maguire et al.   NEW ENGLAND JOURNAL OF MEDICINE