4.6 Article

The Role of Stem Cells in Cutaneous Wound Healing: What Do We Really Know?

Journal

PLASTIC AND RECONSTRUCTIVE SURGERY
Volume 127, Issue 1, Pages 10S-20S

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/PRS.0b013e3181fbe2d8

Keywords

-

Categories

Ask authors/readers for more resources

Wound repair is a complex process involving the orchestrated interaction of multiple growth factors, cytokines, chemokines, and cell types. Dysregulation of this process leads to problems such as excessive healing in the form of keloids and hypertrophic scars and chronic, nonhealing wounds. These issues have broad global implications. Stem cells offer enormous potential for enhancing tissue repair and regeneration following injury. The rapidly developing fields of stem cell biology and skin tissue engineering create translational opportunities for the development of novel stem cell based wound-healing therapies. (Plast. Reconstr. Surg. 127 (Suppl.): 10S, 2011.)

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.6
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Editorial Material Cardiac & Cardiovascular Systems

Repair of ascending aortic aneurysms following cardiac transplantation

Shinichi Fukuhara, Elizabeth H. Stephens, Jason P. Glotzbach, Michael A. Borger

JOURNAL OF CARDIAC SURGERY (2016)

Article Multidisciplinary Sciences

Microfluidic single-cell transcriptional analysis rationally identifies novel surface marker profiles to enhance cell-based therapies

Robert C. Rennert, Michael Januszyk, Michael Sorkin, Melanie Rodrigues, Zeshaan N. Maan, Dominik Duscher, Alexander J. Whittam, Revanth Kosaraju, Michael T. Chung, Kevin Paik, Alexander Y. Li, Michael Findlay, Jason P. Glotzbach, Atul J. Butte, Geoffrey C. Gurtner

NATURE COMMUNICATIONS (2016)

Editorial Material Cardiac & Cardiovascular Systems

Rapid-deployment aortic valves: Do the data support a tipping point?

Jason P. Glotzbach, Stephen H. McKellar

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2017)

Article Engineering, Biomedical

Evolutionary Improvements in the Jarvik 2000 Left Ventricular Assist Device

Craig H. Selzman, Antigone Koliopoulou, Jason P. Glotzbach, Stephen H. McKellar

ASAIO JOURNAL (2018)

Article Cardiac & Cardiovascular Systems

Value-driven cardiac surgery: Achieving perfect care'' after coronary artery bypass grafting

Jason P. Glotzbach, Vikas Sharma, Joseph E. Tonna, Jacob C. Pettit, Stephen H. McKellar, Aaron W. Eckhauser, Thomas K. Varghese, Craig H. Selzman

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2018)

Article Surgery

PHD-2 Suppression in Mesenchymal Stromal Cells Enhances Wound Healing

Sae Hee Ko, Allison C. Nauta, Shane D. Morrison, Michael S. Hu, Andrew S. Zimmermann, Michael T. Chung, Jason P. Glotzbach, Victor W. Wong, Graham G. Walmsley, H. Peter Lorenz, Denise A. Chan, Geoffrey C. Gurtner, Amato J. Giaccia, Michael T. Longaker

PLASTIC AND RECONSTRUCTIVE SURGERY (2018)

Article Immunology

Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension

Hirofumi Sawada, Toshie Saito, Nils P. Nickel, Tero-Pekka Alastalo, Jason P. Glotzbach, Roshelle Chan, Leila Haghighat, Gabriele Fuchs, Michael Januszyk, Aiqin Cao, Ying-Ju Lai, Vinicio de Jesus Perez, Yu-Mee Kim, Lingli Wang, Pin-I Chen, Edda Spiekerkoetter, Yoshihide Mitani, Geoffrey C. Gurtner, Peter Sarnow, Marlene Rabinovitch

JOURNAL OF EXPERIMENTAL MEDICINE (2014)

Article Cell & Tissue Engineering

Tracking the Elusive Fibrocyte: Identification and Characterization of Collagen-Producing Hematopoietic Lineage Cells During Murine Wound Healing

Hirotaka Suga, Robert C. Rennert, Melanie Rodrigues, Michael Sorkin, Jason P. Glotzbach, Michael Januszyk, Toshihiro Fujiwara, Michael T. Longaker, Geoffrey C. Gurtner

STEM CELLS (2014)

Meeting Abstract Cardiac & Cardiovascular Systems

BEYOND THE AORTA: PULMONARY ARTERY DILATION AND IMPACT OF TREATMENT IN MARFAN SYNDROME

Arvind Hoskoppal, Shaji Menon, Ronald Lacro, Lauren Andrade, Luciana Young, Jason Glotzbach, Zhining Ou, L. Luann Minich

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2019)

Article Cardiac & Cardiovascular Systems

Rapid-deployment aortic valve replacement after aortic root replacement: A safe alternative to redo root replacement

Travis J. Wilder, Vikas Sharma, Antigone Koliopoulou, Stephen H. McKellar, Craig H. Selzman, Jason P. Glotzbach

JOURNAL OF CARDIAC SURGERY (2020)

Article Medicine, General & Internal

Evaluation of the Sex-and-Age-Specific Effects of PM2.5 on Hospital Readmission in the Presence of the Competing Risk of Mortality in the Medicare Population of Utah 1999-2009

Claire L. Leiser, Ken R. Smith, James A. VanDerslice, Jason P. Glotzbach, Timothy W. Farrell, Heidi A. Hanson

JOURNAL OF CLINICAL MEDICINE (2019)

Article Cardiac & Cardiovascular Systems

Is timing everything? Bioprosthetic valve fracture in valve-in-valve TAVR

Tara L. Jones, Vikas Sharma, Jason P. Glotzbach, Frederick G. P. Welt, Anwar Tandar

JOURNAL OF CARDIAC SURGERY (2020)

Article Surgery

Predictors of Adherence to Anti-Impulse Therapy among Patients Treated for Acute Type-B Aortic Dissections

Benjamin S. Brooke, Claire L. Griffin, Jason P. Glotzbach, Joshua J. Horns, Shardool Patel, Larry W. Kraiss

Summary: This study evaluated medication adherence among patients treated for acute Type-B aortic dissections and identified factors affecting adherence, such as age, gender, method of medication acquisition, and prescription duration. Results showed that younger female patients were more likely to be nonadherent to their prescribed medications, highlighting the importance of targeted interventions to improve adherence.

ANNALS OF VASCULAR SURGERY (2021)

Review Medicine, General & Internal

Minimally Invasive versus Full Sternotomy SAVR in the Era of TAVR: An Institutional Review

Tyler W. Wilson, Joshua J. Horns, Vikas Sharma, Matthew L. Goodwin, Hiroshi Kagawa, Sara J. Pereira, Stephen H. McKellar, Craig H. Selzman, Jason P. Glotzbach

Summary: In this study, the perioperative variables and postoperative outcomes of minimally invasive and full sternotomy surgical aortic valve replacement were compared. The results showed that there were no significant differences in preoperative comorbidities and demographic information between the two groups. The procedure length was slightly shorter in the minimally invasive group, but not significantly. There were no differences in the incidence of postoperative adverse events between the two groups.

JOURNAL OF CLINICAL MEDICINE (2022)

Article Cardiac & Cardiovascular Systems

Familial Associations of Prevalence and Cause-Specific Mortality for Thoracic Aortic Disease and Bicuspid Aortic Valve in a Large-Population Database

Jason P. Glotzbach, Heidi A. Hanson, Joseph E. Tonna, Joshua J. Horns, Chelsea McCarty Allen, Angela P. Presson, Claire L. Griffin, Megan Zak, Vikas Sharma, Martin Tristani-Firouzi, Craig H. Selzman

Summary: In this large-population study, familial associations of thoracic aortic disease and bicuspid aortic valve (BAV) were examined. The risk of developing the same disease was found to be higher in relatives of patients with BAV, as well as in those with thoracic aortic aneurysm or dissection. Additionally, relatives of individuals with these diagnoses had a higher risk of aortic-specific mortality compared to controls.

CIRCULATION (2023)

No Data Available