Inhibitory mechanisms of celastrol on human liver cytochrome P450 1A2, 2C19, 2D6, 2E1 and 3A4

Identification and characterization of potent CYP2D6 inhibitors in lotus leaves

(2014) Lin-Hu Ye et al.   JOURNAL OF ETHNOPHARMACOLOGY

Development of an in vitro cytochrome P450 cocktail inhibition assay for assessing the inhibition risk of drugs of abuse

(2014) Julia Dinger et al.   TOXICOLOGY LETTERS

Celastrol targets proteostasis and acts synergistically with a heat-shock protein 90 inhibitor to kill human glioblastoma cells

(2014) S Boridy et al.   Cell Death & Disease

Inhibitory effects of celastrol on rat liver cytochrome P450 1A2, 2C11, 2D6, 2E1 and 3A2 activity

(2013) Min Sun et al.   FITOTERAPIA

Selective inhibitory effects of mollugin on CYP1A2 in human liver microsomes

(2012) Heeyeon Kim et al.   FOOD AND CHEMICAL TOXICOLOGY

Oral bioavailability and gender-related pharmacokinetics of celastrol following administration of pure celastrol and its related tablets in rats

(2012) Jun Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

In vitrometabolic interactions between black cohosh (Cimicifuga racemosa) and tamoxifen via inhibition of cytochromes P450 2D6 and 3A4

(2011) Jinghu Li et al.   XENOBIOTICA

Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease

(2009) Katharina Faust et al.   BMC NEUROSCIENCE

The Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of America

(2009) S. W. Grimm et al.   DRUG METABOLISM AND DISPOSITION

Celastrol suppresses allergen-induced airway inflammation in a mouse allergic asthma model

(2009) Dae Yong Kim et al.   EUROPEAN JOURNAL OF PHARMACOLOGY