Journal
PLANTA MEDICA
Volume 80, Issue 15, Pages 1298-1303Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0034-1382995
Keywords
Psoralea corylifolia; Fabaceae; meroterpenes; antifungal; Pyricularia oryzae
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Funding
- Natural Science Foundation of Shanghai [13ZR1441700]
- Xing-lin scholar of SHUTCM
- Eastern Scholar Program
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Six new meroterpenes, namely, 13-methoxyisobakuchiol (1), 13-ethoxyisobakuchiol (2), 12,13dihydro- 13-hydroxybakuchiol (3), Delta(10)-12,13-dihydro- 12-(R, S)-methoxyisobakuchiol (4 and 5), and 15-demetyl-12,13-dihydro-13-ketobakuchiol (6), together with four known ones, namely, Delta(3),2-hydroxybakuchiol (7), Delta(1),3-hydroxybakuchiol (8), bakuchiol (9), and Delta(1,3)-bakuchiol (10), were isolated from the seeds of Psoralea corylifolia. Their structures were identified based on spectral data, including those obtained via 1D and 2D NMR, and MS spectral analyses. Antifungal screening results indicated that all compounds showed moderate inhibitory activities against Pyricularia oryzae.
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