Journal
PLANTA MEDICA
Volume 77, Issue 17, Pages 1950-1957Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1271186
Keywords
Cuscuta chinensis Lam.; Cuscuta australis R. Br.; Convolvulaceae; Chinese herbal medicine; quality control; HPLC-DAD-MS
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Funding
- Peking University Health Science Center [985-2-119-121]
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Cuscuta chinensis and Cuscuta australis, the two botanical sources of the Chinese herbal medicine Tu-Si-Zi, were distinguished from each other based on qualitative and quantitative chemical analysis. By HPLC-DAD-MS, a total of 36 compounds were characterized from these two Cuscuta species, including 14 flavonoids, 17 quinic acid derivatives, and 5 lignans. In addition, HPLC-UV was applied to determine seven major compounds (6 flavonoids plus chlorogenic acid) in 27 batches of Tu-Si-Zi. The results revealed that the amounts of the three classes of compounds varied significantly between the species. C. australis contained more flavonoids but less quinic acid derivatives and lignans than C. chinensis. Particularly, the amounts of kaempferol and astragalin in C. australis were remarkably higher than in C. chinensis. This finding could be valuable for the quality control of Tu-Si-Zi.
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