Article
Biochemistry & Molecular Biology
Catia Garcia, Maria Ines Dias, Marta H. F. Henriques, Lillian Barros, Fernando Ramos
Summary: This study aimed to develop a new wine spirit beverage using almond shells and flowers of P. tridentatum for further characterization of bioactive and phenolic compounds. It also evaluated the acceptance of this new product by the market through a sensorial study. The results showed that the developed liqueur and wine spirits had distinct physicochemical properties and were well-received by consumers.
Article
Chemistry, Applied
Christof B. Steingass, Jonas Burkhardt, Vicky Baeumer, Keshav Kumar, Heiko Mibus-Schoppe, Jana Zinkernagel, Patricia Esquivel, Victor M. Jimenez, Ralf Schweiggert
Summary: Anthocyanins were characterized in red cabbage, sweet potato, and Tradescantia pallida leaves. Various non-, mono-, and diacylated cyanidins were identified in red cabbage. Sweet potato leaves contained mono- and diacylated cyanidin- and peonidin glycosides, while T. pallida leaves mainly contained tetra-acylated anthocyanin tradescantin. The thermal stability of red cabbage and purple sweet potato extracts surpassed that of a commercial food dye, but still fell short compared to the stability of Tradescantia extract.
Article
Food Science & Technology
Yara Paula Nishiyama-Hortense, Carolina Olivati, Jose Perez-Navarro, Reginaldo Teodoro Souza, Natalia S. Janzantti, Roberto Da-Silva, Isidro Hermosin-Gutierrez, Sergio Gomez-Alonso, Ellen Silva Lago-Vanzela
Summary: The study aimed to determine the phenolic compounds in the edible parts of BRS Carmem grapes harvested at two different stages of maturation. It was found that both mature and immature grapes contained high amounts of flavonols, anthocyanins, hydroxycinnamic acids derivatives, and stilbenes. The concentrations of these compounds were higher in the whole grapes compared to their skins, and higher in the seeds compared to the skins. Despite being immature, BRS Carmem grapes still exhibited a complex phenolic composition.
Article
Biochemistry & Molecular Biology
Yu-Zhu Yang, Tao Wang, Qi-Lei Chen, Hu-Biao Chen, Qian-Song He, Ya-Zhou Zhang
Summary: Astragalus membranaceus, a traditional Chinese medicine, has medicinal and edible uses in China. It is increasingly used in the prevention of hypertension, cerebral ischemia, and stroke. The important components, formononetin and ononin, may play significant roles in the treatment of cardiovascular diseases (CVDs). Metabolic studies were conducted on formononetin and ononin, revealing their metabolic pathways and identified metabolites. The main metabolites of formononetin were hydroxylation, demethylation, and glycosylation, while the main metabolites of ononin were glucuronidation, hydroxylation, demethylation, and sulfonation. These metabolites showed potential cardiovascular activities and strong binding affinities with specific receptors related to CVDs.
Article
Food Science & Technology
Antonio Costa-Perez, Diego A. Moreno, Paula M. Periago, Cristina Garcia-Viguera, Raul Dominguez-Perles
Summary: The stalks of broccoli contain a significant amount of bioactive compounds, such as (poly)phenols and glucosinolates, which have antioxidant and anti-inflammatory properties. This study aimed to develop a new ingredient rich in these bioactive compounds from broccoli stalks and evaluate its bioaccessibility. The findings showed that low-temperature stabilization of the core samples provided the highest content of bioactives, including antioxidant phenolics and sulforaphane. These results suggest the potential for using broccoli stalks as a source of functional ingredients with health benefits.
Article
Agricultural Engineering
Catarina Andrade, Federico Ferreres, Nelson G. M. Gomes, Angel Gil-Izquierdo, Sutsawat Duangsrisai, David M. Pereira, Paula B. Andrade, Patricia Valentao
Summary: The leaves of Chukrasia tabularis are rich in phenolic compounds with great potential to improve metabolic disorders. They can be used for the development of new drugs to improve glycemic, oxidative, and inflammatory markers in diabetic patients.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Chemistry, Applied
Catarina Silva, Jose S. Camara, Rosa Perestrelo
Summary: Tropical fruits are rich in phenolic compounds that have antioxidant properties. A high throughput analytical method successfully established the phenolic profile of tropical fruits, with flavonols being the predominant chemical group. The research findings provide insights into the bioactive potential of tropical fruits, but in vivo experiments are necessary to understand their health-promoting properties.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2021)
Article
Chemistry, Applied
Zahra Gharari, Khadijeh Bagheri, Behnam Derakhshani, Ali Sharafi
Summary: In this study, the phenolic compounds of three traditional Iranian herbs were analyzed using HPLC-DAD-ESI/MSn. The major flavonoids of the Scutellaria genus and other flavonoid compounds and phenylethanoid glycosides were identified. These herbs were found to be a potential source of bioactive metabolites.
NATURAL PRODUCT RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Raquel Costa, Daniela Azevedo, Pedro Barata, Raquel Soares, Luis F. Guido, Daniel O. Carvalho
Summary: The study demonstrated that the purple acai hydroethanolic extract (AHE) possesses antiangiogenic properties, reducing the migration and invasion potential of human microvascular endothelial cells (HMEC-1) and inhibiting the formation of capillary-like structures. Additionally, it enhanced antioxidant defenses by upregulating enzymatic activities of superoxide dismutase and catalase, while decreasing reactive oxygen species production. These findings suggest the potential application of AHE in developing novel therapeutic approaches for angiogenesis-dependent diseases.
Article
Plant Sciences
Soraia I. Pedro, Tiago A. Fernandes, Angelo Luis, Alexandra M. M. Antunes, Jose C. Goncalves, Jorge Gominho, Eugenia Gallardo, Ofelia Anjos
Summary: This study evaluated the potential industrial applications of various Acacia species by examining their chemical composition, antioxidant, and antimicrobial properties. Among the studied species, A. pycnantha exhibited a higher concentration of total phenolic compounds and displayed notable antibacterial activity. Vibrational spectroscopy was a reliable method for distinguishing between species.
Article
Chemistry, Analytical
Jinxin Zhou, Sheng Yu, Bingqian Wang, Xing Wei, Li Zhang, Mingqiu Shan
Summary: Yihuang decoction (YHD), a famous traditional Chinese medicine formula, has been used for centuries to treat gynecological diseases. This study employed HPLC-Q-TOF-MS to analyze the chemical composition of YHD and identified 90 components, including alkaloids, organic acids, glycosides, flavonoids, and amino acids. Furthermore, HPLC-DAD was used to determine the content of 8 representative compounds in YHD samples, showing good linearity and precision. This study provides comprehensive chemical profiling of YHD and serves as a basis for quality control and understanding its mechanism of action.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2023)
Article
Chemistry, Applied
Zijian Liang, Pangzhen Zhang, Yun Xiong, Stuart K. Johnson, Zhongxiang Fang
Summary: This study characterized the phenolic and carotenoid profiles of the Australian native bulb plant, Haemodorum spicatum, using HPLC-DAD-ESI-QTOF-MS/MS and HPLC-DAD. The results identified 40 phenolic compounds and 2 carotenoids, with 35 compounds being reported for the first time in H. spicatum.
Article
Chemistry, Multidisciplinary
Benedict Carius, Helena Silva, Artur M. S. Silva, Diana C. G. A. Pinto
Summary: This study established the chemical profile of Limonium vulgare's aerial parts, revealing a richness in fatty acids, alkanes, terpenoids, and flavonoids. The species is found to be a promising source of bioactive compounds, particularly myricetin derivatives and quercetin, which could be utilized for the production of nutraceuticals and pharmaceuticals.
APPLIED SCIENCES-BASEL
(2022)
Article
Chemistry, Applied
Hasya Nazli Gok, Simon Vlad Luca, Saadet Tugrul Ay, Lukasz Komsta, Ramin Ekhteiari Salmas, Ilkay Erdogan Orhan, Krystyna Skalicka-Wozniak
Summary: The ethanol extracts of five Origanum species showed significant cholinesterase inhibition and antioxidant effects, with the phytochemical composition of 60 extracts analyzed. The study also identified a correlation between certain compounds and bioactivity. Additionally, molecular docking data suggested that caffeoylarbutin had the lowest binding energy against both AChE and BChE.
Article
Plant Sciences
Weronika Skowronska, Sebastian Granica, Magdalena Dziedzic, Justyna Kurkowiak, Maria Ziaja, Agnieszka Bazylko
Summary: This study compared the anti-lipoxygenase and antioxidant activity of ethanolic extracts from the aerial parts and roots of Arctium lappa and Arctium tomentosum. The results showed that the extracts from Arctium lappa plant materials exhibited stronger scavenging of reactive oxygen species and a significantly higher content of polyphenolic compounds compared to the extracts from Arctium tomentosum plant materials.
Article
Chemistry, Analytical
Xue Qiao, Xiong-hao Lin, Shuai Ji, Zheng-xiang Zhang, Tao Bo, De-an Guo, Min Ye
ANALYTICAL CHEMISTRY
(2016)
Article
Biochemical Research Methods
Xue Qiao, Ru Li, Wei Song, Wen-juan Miao, Jia Liu, Hu-biao Chen, De-an Guo, Min Ye
JOURNAL OF CHROMATOGRAPHY A
(2016)
Article
Biochemical Research Methods
Qi Wang, Wei Song, Xue Qiao, Shuai Ji, Yi Kuang, Zheng-xiang Zhang, Tao Bo, De-an Guo, Min Ye
JOURNAL OF CHROMATOGRAPHY A
(2016)
Article
Biochemical Research Methods
Xue Qiao, Qi Wang, Wei Song, Yi Qian, Yao Xiao, Rong An, De-an Guo, Min Ye
JOURNAL OF CHROMATOGRAPHY A
(2016)
Article
Biochemical Research Methods
Jing Cao, Hong-Mei Shen, Qi Wang, Yi Qian, Hong-Cheng Guo, Kai Li, Xue Qiao, De-An Guo, Xiao-Dong Luo, Min Ye
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2016)
Article
Plant Sciences
Shuai Ji, Ziwei Li, Wei Song, Yongrui Wang, Wenfei Liang, Kai Li, Shunan Tang, Qi Wang, Xue Qiao, Demin Zhou, Siwang Yu, Min Ye
JOURNAL OF NATURAL PRODUCTS
(2016)
Article
Pharmacology & Pharmacy
Wenzhi Yang, Xue Qiao, Kai Li, Jingran Fan, Tao Bo, De-an Guo, Min Ye
ACTA PHARMACEUTICA SINICA B
(2016)
Article
Plant Sciences
Kai Li, Shuai Ji, Wei Song, Yi Kuang, Yan Lin, Shunan Tang, Zexu Cui, Xue Qiao, Siwang Yu, Min Ye
JOURNAL OF NATURAL PRODUCTS
(2017)
Article
Plant Sciences
Yi Kuang, Yan Lin, Kai Li, Wei Song, Shuai Ji, Xue Qiao, Qingying Zhang, Min Ye
Article
Pharmacology & Pharmacy
Shuai Ji, Shunan Tang, Kai Li, Ziwei Li, Wenfei Liang, Xue Qiao, Qi Wang, Siwang Yu, Min Ye
TOXICOLOGY AND APPLIED PHARMACOLOGY
(2017)
Article
Multidisciplinary Sciences
Xue Qiao, Qi Wang, Shuang Wang, Wen-juan Miao, Yan-jiao Li, Cheng Xiang, De-an Guo, Min Ye
SCIENTIFIC REPORTS
(2016)
Article
Biochemistry & Molecular Biology
Yan Lin, Yi Kuang, Kai Li, Shuang Wang, Shuai Ji, Kuan Chen, Wei Song, Xue Qiao, Min Ye
BIOORGANIC & MEDICINAL CHEMISTRY
(2017)
Article
Biochemistry & Molecular Biology
Yan Lin, Yi Kuang, Kai Li, Shuang Wang, Wei Song, Xue Qiao, Gulnar Sabir, Min Ye
BIOORGANIC & MEDICINAL CHEMISTRY
(2017)
Article
Chemistry, Applied
Jin Feng, Peng Zhang, Yinglu Cui, Kai Li, Xue Qiao, Ying-Tao Zhang, Shu-Ming Li, Russell J. Cox, Bian Wu, Min Ye, Wen-Bing Yin
ADVANCED SYNTHESIS & CATALYSIS
(2017)
Article
Chemistry, Analytical
Wei Song, Xue Qiao, Kuan Chen, Ying Wang, Shuai Ji, Jin Feng, Kai Li, Yan Lin, Min Ye
ANALYTICAL CHEMISTRY
(2017)
