Interleukin-22 ameliorates liver fibrogenesis by attenuating hepatic stellate cell activation and downregulating the levels of inflammatory cytokines

Impaired balance of T helper 17/T regulatory cells in carbon tetrachloride-induced liver fibrosis in mice

(2014) Xiao-Fei Sun   WORLD JOURNAL OF GASTROENTEROLOGY

IFN-γ inhibits liver progenitor cell proliferation in HBV-infected patients and in 3,5-diethoxycarbonyl-1,4-dihydrocollidine diet-fed mice

(2013) Hong-lei Weng et al.   JOURNAL OF HEPATOLOGY

IL-17A Plays a Critical Role in the Pathogenesis of Liver Fibrosis through Hepatic Stellate Cell Activation

(2013) Z. Tan et al.   JOURNAL OF IMMUNOLOGY

Interleukin-17A plays a pivotal role in cholestatic liver fibrosis in mice

(2013) Michio Hara et al.   JOURNAL OF SURGICAL RESEARCH

Th17 Cells Regulate Liver Fibrosis by Targeting Multiple Cell Types: Many Birds With One Stone

(2012) Bin Gao et al.   GASTROENTEROLOGY

Inhibition of Interleukin-17 Promotes Differentiation of CD25– Cells Into Stable T Regulatory Cells in Patients With Autoimmune Hepatitis

(2012) Maria Serena Longhi et al.   GASTROENTEROLOGY

Interleukin-17 Signaling in Inflammatory, Kupffer Cells, and Hepatic Stellate Cells Exacerbates Liver Fibrosis in Mice

(2012) Fanli Meng et al.   GASTROENTEROLOGY

Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice

(2012) Xiaoni Kong et al.   HEPATOLOGY

Glycyrrhizin regulates CD4+T cell response during liver fibrogenesis via JNK, ERK and PI3K/AKT pathway

(2012) Chuan-tao Tu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Increased Th17 cells contribute to disease progression in patients with HBV-associated liver cirrhosis

(2012) H. Q. Sun et al.   JOURNAL OF VIRAL HEPATITIS

Interleukin-22

(2012) Paul J. Chestovich et al.   TRANSPLANTATION

Increased Expressions of IL-22 and Th22 cells in the coxsackievirus B3-Induced mice acute viral myocarditis

(2012) Qing Kong et al.   Virology Journal

IL-22 Protects Against Liver Pathology and Lethality of an Experimental Blood-Stage Malaria Infection

(2012) Béatris Mastelic et al.   Frontiers in Immunology

The balance between intrahepatic IL-17+ T cells and Foxp3+ regulatory T cells plays an important role in HBV-related end-stage liver disease

(2011) Yinghua Niu et al.   BMC IMMUNOLOGY

Modulation of CD4+ T cell responses following splenectomy in hepatitis C virus-related liver cirrhosis

(2011) N. Hashimoto et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Hepatoprotective effects of IL-22 on fulminant hepatic failure induced by d-galactosamine and lipopolysaccharide in mice

(2011) Wei-wei Xing et al.   CYTOKINE

In vivo consequences of liver-specific interleukin-22 expression in mice: Implications for human liver disease progression

(2011) Ogyi Park et al.   HEPATOLOGY

Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor C-C motif chemokine receptor 8 in mice

(2011) Felix Heymann et al.   HEPATOLOGY

Th17 and Regulatory T Cells in Mediating and Restraining Inflammation

(2010) Dan R. Littman et al.   CELL

Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: Role of signal transducer and activator of transcription 3

(2010) Sung Hwan Ki et al.   HEPATOLOGY

Amelioration of high fat diet induced liver lipogenesis and hepatic steatosis by interleukin-22

(2010) Ling Yang et al.   JOURNAL OF HEPATOLOGY

Decreased Ratio of Treg Cells to Th17 Cells Correlates with HBV DNA Suppression in Chronic Hepatitis B Patients Undergoing Entecavir Treatment

(2010) Ji-Yuan Zhang et al.   PLoS One

IL-22 is involved in liver regeneration after hepatectomy

(2009) Xiaodan Ren et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Critical Regulation of Early Th17 Cell Differentiation by Interleukin-1 Signaling

(2009) Yeonseok Chung et al.   IMMUNITY

Implication of Th17 and Th1 Cells in Patients with Chronic Active Hepatitis B

(2009) Jian Ge et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells

(2009) Sara Trifari et al.   NATURE IMMUNOLOGY

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells

(2009) Thomas Duhen et al.   NATURE IMMUNOLOGY

Interleukin-17 and Type 17 Helper T Cells

(2009) Pierre Miossec et al.   NEW ENGLAND JOURNAL OF MEDICINE

IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation

(2009) S. Z. Ben-Sasson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immune Interactions in Hepatic Fibrosis

(2008) Andrew P. Holt et al.   Clinics in Liver Disease

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

The interleukin-17 pathway is involved in human alcoholic liver disease

(2008) Arnaud Lemmers et al.   HEPATOLOGY

Chemokine-directed immune cell infiltration in acute and chronic liver disease

(2008) Karlin Raja Karlmark et al.   Expert Review of Gastroenterology & Hepatology