Article
Multidisciplinary Sciences
Irene Robles-Rebollo, Sergi Cuartero, Adria Canellas-Socias, Sarah Wells, Mohammad M. Karimi, Elisabetta Mereu, Alexandra G. Chivu, Holger Heyn, Chad Whilding, Dirk Dormann, Samuel Marguerat, Inmaculada Rioja, Rab K. Prinjha, Michael P. H. Stumpf, Amanda G. Fisher, Matthias Merkenschlager
Summary: This study demonstrates that inducible genes and enhancers are mainly regulated by transcriptional burst frequency, which is coordinated in single cells and individual alleles. Cohesin is required for coupling burst frequencies of inducible enhancers and promoters, but not for regulating enhancer burst frequencies. The results also suggest that cohesin and BD2 may act on shared pathways in enhancer-mediated inducible gene expression.
NATURE COMMUNICATIONS
(2022)
Review
Plant Sciences
Fei Gao, Christian Dubos
Summary: Plants tightly control iron uptake, translocation, assimilation, and storage through complex transcriptional regulatory networks, with the bHLH family of transcription factors playing a vital role. Research also involves other classes of transcription factors and post-translational mechanisms. Future research aims to further understand how plants precisely regulate iron homeostasis.
JOURNAL OF EXPERIMENTAL BOTANY
(2021)
Article
Multidisciplinary Sciences
Alexander Plong, Kevin Rodriguez, Mark Alber, Weitao Chen, G. Venugopala Reddy
Summary: WUSCHEL concentration regulation is crucial for stem cell homeostasis in Arabidopsis shoot apical meristems. CLAVATA3 not only represses WUSCHEL transcription, but also regulates WUSCHEL by controlling its nuclear export and diffusion between adjacent cells.
NATURE COMMUNICATIONS
(2021)
Article
Biochemistry & Molecular Biology
Zhuo Huang, Si-Han Jin, Li Yang, Li Song, Yuan-Hong Wang, Lin-Li Jian, Cai-Zhong Jiang
Summary: The study isolated a dehydration-inducible bHLH transcription factor gene MfbHLH145 from M. flabellifolia, which enhanced drought and salt tolerance in Arabidopsis. MfbHLH145 contributes to enhanced leaf water retention capacity through the promotion of stomatal closure, increased osmolyte accumulation, and increased antioxidant enzyme activities.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Kurni Kurniyati, Yunjie Chang, Jun Liu, Chunhao Li
Summary: This study investigates the role of multiple flagellin proteins using Treponema denticola as a model. The flagellar filaments of T. denticola are mainly composed of four proteins, regulated by different transcription factors. Each flagellin protein contributes to spirochete motility, and FlaA forms a seam-like structure. These findings demonstrate the unique regulation and assembly mechanism of flagellar filament in T. denticola.
MOLECULAR MICROBIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Fa Dai, Ming Guo, Yina Shao, Chenghua Li
Summary: The study revealed that the flagellum protein of Vibrio splendidus destroyed tissue structure and promoted apoptosis in sea cucumber, with the novel receptor AjTmod playing a role in activating the p38 MAPK signaling pathway to induce p53-dependent coelomocyte apoptosis in Echinodermata.
JOURNAL OF BIOLOGICAL CHEMISTRY
(2022)
Article
Biotechnology & Applied Microbiology
Yongil Yang, Jun Hyung Lee, Magen R. Poindexter, Yuanhua Shao, Wusheng Liu, Scott C. Lenaghan, Amir H. Ahkami, Eduardo Blumwald, Charles Neal Stewart
Summary: Researchers identified five synthetic promoters in hybrid poplar that showed better inducibility under abiotic stress conditions compared to native promoters, demonstrating the potential of synthetic biology in producing transgenic plants with improved stress resistance traits.
PLANT BIOTECHNOLOGY JOURNAL
(2021)
Article
Neurosciences
Daniel Bormann, Dragan Copic, Katharina Klas, Martin Direder, Christian J. Riedl, Giulia Testa, Hannes Kuehtreiber, Emilia Poreba, Simon Hametner, Bahar Golabi, Melanie Salek, Carmen Haider, Verena Endmayr, Lisa E. Shaw, Romana Hoeftberger, Hendrik J. Ankersmit, Michael Mildner
Summary: This study investigated the acute responses of the mammalian brain to bacterial and viral PAMP challenges. It found shared and distinct responses in brain vascular and ependymal cells, limited neuronal response to PAMPs, and a pronounced dependency of oligodendrocytes on IFN stimulation during viral PAMP challenges.
NEUROBIOLOGY OF DISEASE
(2023)
Article
Chemistry, Analytical
Devendra Bhandari, Fur-Chi Chen, Roger C. Bridgman
Summary: This study developed a method utilizing magnetic nanoparticles and surface plasmon resonance for rapid detection of Salmonella. The results showed that the sequential two-step sandwich assay and preincubation one-step sandwich assay had higher detection signals compared to the direct assay, with detection limits reaching a high level.
Article
Plant Sciences
Yongil Yang, Yuanhua Shao, Timothy A. Chaffin, Jun Hyung Lee, Magen R. Poindexter, Amir H. Ahkami, Eduardo Blumwald, C. Neal Stewart Jr
Summary: Generating resistant crops to abiotic stresses is crucial for sustainable bioenergy crop production. This study developed synthetic drought stress-inducible promoters to control the precise expression of stress resistance genes in transgenic poplar, and found that shorter synthetic promoters can be used for versatile control of gene expression.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Biochemical Research Methods
Yanling Wu, Jiliang Deng, Zhaohui Zheng, Nanzhu Chen, Xiaozhou Luo, Hongting Tang
Summary: In this study, the activation effects of Gal4p activators from different yeasts or fungi on a variant of GAL promoters were comprehensively characterized. It was found that expression of KlLac9p from Kluyveromyces lactis increased the activity of P-ScGAL1 and P-SkGAL2 and evaded Gal80p inhibition. This optimized GAL expression system significantly enhanced the production of beta-carotene in S. cerevisiae.
ACS SYNTHETIC BIOLOGY
(2023)
Article
Plant Sciences
Haibo Yang, Pengcheng Zhang, Diandian Guo, Na Wang, Hao Lin, Xingchun Wang, Lifang Niu
Summary: The MADS-box gene family, particularly the AP1/FUL subfamily, plays significant roles in regulating plant reproductive development. However, the role of AGL79, the homologue of the AP1/FUL subfamily in Arabidopsis thaliana, has not been well understood. In this study, the researchers discovered that AGL79 acts as a transcriptional repressor and positively regulates flowering time in Arabidopsis.
JOURNAL OF PLANT PHYSIOLOGY
(2023)
Article
Plant Sciences
Stefanie Menezes de Moura, Elinea Oliveira Freitas, Thuanne Pires Ribeiro, Bruno Paes-de-Melo, Fabricio B. M. Arraes, Leonardo Lima Pepino Macedo, Joaquin F. R. Paixao, Isabela T. Lourenco-Tessutti, Sinara Artico, David da Cunha Valenca, Maria Cristina Mattar Silva, Antonio C. de Oliveira, Marcio Alves-Ferreira, Maria Fatima Grossi-de-Sa
Summary: This study selected the GhERF105 and GhNc-HARBI1 genes based on transcriptome-wide data from cotton plants infested by CBW larvae and evaluated their promoter regions. The pGhERF105 and pGhNc-HARBI1 promoters showed strong activity in plant vegetative and reproductive tissues, making them suitable for biotechnological application in cotton plants for pest resistance.
PLANT CELL REPORTS
(2022)
Article
Plant Sciences
Katharina Bursch, Ella T. Niemann, David C. Nelson, Henrik Johansson
Summary: The butenolide molecule karrikin (KAR) enhances light responses in Arabidopsis through a signaling pathway involving KAI2, MAX2, SMAX1, SMXL2, HY5, BBX20, and BBX21. This pathway is responsible for regulating hypocotyl elongation and anthocyanin accumulation, with the HY5-BBX module playing a crucial role in mediating these responses. Light- and KAR-dependent signaling intersect at the HY5-BBX transcriptional module.
Article
Plant Sciences
Haruki Onosato, Genya Fujimoto, Tomota Higami, Takuya Sakamoto, Ayaka Yamada, Takamasa Suzuki, Rika Ozawa, Sachihiro Matsunaga, Motoaki Seki, Minoru Ueda, Kaori Sako, Ivan Galis, Gen-ichiro Arimura
Summary: Plant volatile signaling triggers defense responses by epigenetic transcriptional regulation of ethylene response factor genes to sustain anti-herbivore traits. These defense abilities are maintained for 5 days after exposure to β-ocimene, correlated with the expression levels of genes.
Article
Environmental Sciences
Xunde Li, Edward R. Atwill, Elizabeth Antaki, Olin Applegate, Brian Bergamaschi, Ronald F. Bond, Jennifer Chase, Katherine M. Ransom, William Samuels, Naoko Watanabe, Thomas Harter
JOURNAL OF ENVIRONMENTAL QUALITY
(2015)
Article
Biotechnology & Applied Microbiology
Edward R. Atwill, Jennifer A. Chase, David Oryang, Ronald F. Bond, Steven T. Koike, Michael D. Cahn, Maren Anderson, Amirhossein Mokhtari, Sherri Dennis
JOURNAL OF FOOD PROTECTION
(2015)
Article
Environmental Sciences
Melissa L. Partyka, Ronald F. Bond, Jennifer A. Chase, Luana Kiger, Edward R. Atwill
JOURNAL OF ENVIRONMENTAL QUALITY
(2016)
Article
Biotechnology & Applied Microbiology
Jennifer A. Chase, Edward R. Atwill, Melissa L. Partyka, Ronald F. Bond, David Oryang
JOURNAL OF FOOD PROTECTION
(2017)
Article
Environmental Sciences
Melissa L. Partyka, Ronald F. Bond, Jennifer A. Chase, Edward R. Atwill
SCIENCE OF THE TOTAL ENVIRONMENT
(2017)
Article
Engineering, Environmental
Melissa L. Partyka, Ronald F. Bond, Jennifer A. Chase, Edward R. Atwill
Article
Environmental Sciences
David J. Lewis, Edward R. Atwill, Maria das Gracas C. Pereira, Ronald Bond
JOURNAL OF ENVIRONMENTAL QUALITY
(2013)
Article
Environmental Sciences
Melissa L. Partyka, Ronald F. Bond, Jennifer A. Chase, Edward R. Atwill
JOURNAL OF ENVIRONMENTAL QUALITY
(2018)
Article
Biotechnology & Applied Microbiology
Melissa L. Partyka, Ronald F. Bond, Jeff Farrar, Andy Falco, Barbara Cassens, Alonza Cruse, Edward R. Atwill
JOURNAL OF FOOD PROTECTION
(2014)
Article
Multidisciplinary Sciences
Jennifer A. Chase, Melissa L. Partyka, Ronald F. Bond, Edward R. Atwill
Article
Environmental Sciences
Xunde Li, Jennifer A. Chase, Ronald F. Bond, Panachon Lor, Kristine Fernandez, Tran H. Nguyen, Melissa L. Partyka, Anyarat Thiptara, Edward R. Atwill
ENVIRONMENTAL MONITORING AND ASSESSMENT
(2019)
Article
Infectious Diseases
Madeline M. McCuen, Maurice E. Pitesky, Jeffrey J. Buler, Sarai Acosta, Alexander H. Wilcox, Ronald F. Bond, Samuel L. Diaz-Munoz
Summary: The study identified two high waterfowl density areas in California using NEXRAD and tested the efficacy of two ultrafiltration methods and two nucleic acid based AIv detection assays. Whole-segment amplification and long-read sequencing were more effective at detecting AIv compared to standard methods. The study also found mismatches between published primers and samples which could lead to a failure in detecting many of the currently sequenced AIv genomes in public databases.
TRANSBOUNDARY AND EMERGING DISEASES
(2021)
Review
Environmental Sciences
Melissa L. Partyka, Ronald F. Bond
Summary: This article discusses the risks and methods for reducing risks associated with irrigation of ready-to-eat produce using reuse water. Although there is little evidence to suggest that adequately treated reuse water poses more risk than other sources of irrigation water, guidelines should be regionally specific and consider factors such as local growing practices and population health.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Biotechnology & Applied Microbiology
Xiaohong Wei, Amlan Aggrawal, Ronald F. Bond, Brooke C. Latack, Edward R. Atwill
Summary: This study evaluated the occurrence of airborne Escherichia coli in proximity to commercial beef cattle feedlots in Imperial Valley, California. The results showed that the detection of E. coli was associated with close proximity to the feedlots and little to no wind. This pilot study found limited dispersal of airborne E. coli in this produce-growing region of California.
JOURNAL OF FOOD PROTECTION
(2023)
Article
Microbiology
Xiaohong Wei, Amlan Aggrawal, Ronald F. Bond, Edward R. Atwill
Summary: This study examined the impact of distance from beef cattle feedlots, environmental factors, and climate on the presence of airborne bacterial indicators and pathogens. Air samples were collected from five feedlots over a 6-month period, and tested for the presence of E. coli O157, non-O157-Shiga toxin-producing E. coli (STEC), Salmonella, and E. coli. Although no bacterial pathogens were detected, E. coli was found in 16.7% of the samples, with a mean concentration of 0.17 CFU/6000 L air. Logistic regression analysis revealed a higher likelihood of E. coli presence in samples closer to the feedlots, as well as associations with meteorological factors and dust-generating activities. This study provides valuable data for future revisions of produce-safety guidance.