Precise plant breeding using new genome editing techniques: opportunities, safety and regulation in the EU

Risk Assessment and Regulation of Molecular Farming - A Comparison between Europe and US

(2013) Penelope Sparrow et al.   CURRENT PHARMACEUTICAL DESIGN

TALEN or Cas9 – Rapid, Efficient and Specific Choices for Genome Modifications

(2013) Chuanxian Wei et al.   Journal of Genetics and Genomics

Europe should rethink its stance on GM crops

(2013) Brian Heap   NATURE

Comparative regulatory approaches for groups of new plant breeding techniques

(2013) Maria Lusser et al.   New Biotechnology

Engineering nucleases for gene targeting: safety and regulatory considerations

(2013) Katia Pauwels et al.   New Biotechnology

In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites

(2013) Jeffry D. Sander et al.   NUCLEIC ACIDS RESEARCH

Targeted molecular trait stacking in cotton through targeted double-strand break induction

(2013) Kathleen D'Halluin et al.   PLANT BIOTECHNOLOGY JOURNAL

Site-directed nucleases: a paradigm shift in predictable, knowledge-based plant breeding

(2013) Nancy Podevin et al.   TRENDS IN BIOTECHNOLOGY

Extensive Natural Epigenetic Variation at a De Novo Originated Gene

(2013) Amanda Bortolini Silveira et al.   PLoS Genetics

Transgenic or not? No simple answer!

(2012) Nancy Podevin et al.   EMBO REPORTS

Agnostic about agriculture

(2012)   NATURE BIOTECHNOLOGY

Existing agbiotech traits continue global march

(2012) Andrew Marshall   NATURE BIOTECHNOLOGY

Tiptoeing around transgenics

(2012) Emily Waltz   NATURE BIOTECHNOLOGY

Deployment of new biotechnologies in plant breeding

(2012) Maria Lusser et al.   NATURE BIOTECHNOLOGY

Reverse breeding in Arabidopsis thaliana generates homozygous parental lines from a heterozygous plant

(2012) Erik Wijnker et al.   NATURE GENETICS

Field trials and tribulations-making sense of the regulations for experimental field trials of transgenic crops in Europe

(2012) Sonia Gómez-Galera et al.   PLANT BIOTECHNOLOGY JOURNAL

Genome modifications in plant cells by custom-made restriction enzymes

(2012) Tzvi Tzfira et al.   PLANT BIOTECHNOLOGY JOURNAL

In planta gene targeting

(2012) F. Fauser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Genetic and epigenetic regulation of stress responses in natural plant populations

(2011) Clícia Grativol et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Global food security and the governance of modern biotechnologies

(2011) Joyce Tait et al.   EMBO REPORTS

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

(2011) Vikram Pattanayak et al.   NATURE METHODS

Targeted Mutagenesis of Duplicated Genes in Soybean with Zinc-Finger Nucleases

(2011) S. J. Curtin et al.   PLANT PHYSIOLOGY

Permanent genome modifications in plant cells by transient viral vectors

(2011) Alexander Vainstein et al.   TRENDS IN BIOTECHNOLOGY

Cloning whole bacterial genomes in yeast

(2010) Gwynedd A. Benders et al.   NUCLEIC ACIDS RESEARCH

Zinc finger nuclease-mediated transgene deletion

(2010) Joseph F. Petolino et al.   PLANT MOLECULAR BIOLOGY

Nontransgenic Genome Modification in Plant Cells

(2010) I. Marton et al.   PLANT PHYSIOLOGY

Breaking news: Plants mutate right on target

(2010) H. Puchta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Site-directed mutagenesis in Arabidopsis using custom-designed zinc finger nucleases

(2010) K. Osakabe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-frequency modification of plant genes using engineered zinc-finger nucleases

(2009) Jeffrey A. Townsend et al.   NATURE

Precise genome modification in the crop species Zea mays using zinc-finger nucleases

(2009) Vipula K. Shukla et al.   NATURE

Transient co-expression for fast and high-yield production of antibodies with human-likeN-glycans in plants

(2009) Louis-P. Vézina et al.   PLANT BIOTECHNOLOGY JOURNAL

ZFN-induced mutagenesis and gene-targeting in Arabidopsis throughAgrobacterium-mediated floral dip transformation

(2009) Sylvia de Pater et al.   PLANT BIOTECHNOLOGY JOURNAL

Reverse breeding: a novel breeding approach based on engineered meiosis

(2009) Rob Dirks et al.   PLANT BIOTECHNOLOGY JOURNAL

Targeted transgene integration in plant cells using designed zinc finger nucleases

(2009) Charles Q. Cai et al.   PLANT MOLECULAR BIOLOGY

Exchange of Genetic Material Between Cells in Plant Tissue Grafts

(2009) S. Stegemann et al.   SCIENCE

Creating Bacterial Strains from Genomes That Have Been Cloned and Engineered in Yeast

(2009) C. Lartigue et al.   SCIENCE

The Economics of Genetically Modified Crops

(2009) Matin Qaim   Annual Review of Resource Economics

Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends

(2008) Zhu Zhu et al.   CELL

GM directive deficiencies in the European Union. The current framework for regulating GM crops in the EU weakens the precautionary principle as a policy tool

(2008) Shane H Morris et al.   EMBO REPORTS

An overview of general features of risk assessments of genetically modified crops

(2008) Wendy Craig et al.   EUPHYTICA

Viral vectors for production of recombinant proteins in plants

(2008) Chiara Lico et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Transient expression of chicken alpha interferon gene in lettuce

(2008) Song Li et al.   Journal of Zhejiang University-SCIENCE B

Managing meiotic recombination in plant breeding

(2008) E WIJNKER et al.   TRENDS IN PLANT SCIENCE

DNA-binding Specificity Is a Major Determinant of the Activity and Toxicity of Zinc-finger Nucleases

(2007) Tatjana I Cornu et al.   MOLECULAR THERAPY