SMG1 is an ancient nonsense-mediated mRNA decay effector

An unusual arrangement of two 14-3-3-like domains in the SMG5-SMG7 heterodimer is required for efficient nonsense-mediated mRNA decay

(2013) S. Jonas et al.   GENES & DEVELOPMENT

Plant nonsense-mediated mRNA decay is controlled by different autoregulatory circuits and can be induced by an EJC-like complex

(2013) Tünde Nyikó et al.   NUCLEIC ACIDS RESEARCH

BAIUCAS: a novel BLAST-based algorithm for the identification of upstream open reading frames with conserved amino acid sequences and its application to the Arabidopsis thaliana genome

(2012) Hiro Takahashi et al.   BIOINFORMATICS

MRE11 and RAD50, but not NBS1, are essential for gene targeting in the moss Physcomitrella patens

(2012) Yasuko Kamisugi et al.   NUCLEIC ACIDS RESEARCH

Aberrant growth and lethality of Arabidopsis deficient in nonsense-mediated RNA decay factors is caused by autoimmune-like response

(2012) Nina Riehs-Kearnan et al.   NUCLEIC ACIDS RESEARCH

SMG5–PNRC2 is functionally dominant compared with SMG5–SMG7 in mammalian nonsense-mediated mRNA decay

(2012) Hana Cho et al.   NUCLEIC ACIDS RESEARCH

The late steps of plant nonsense-mediated mRNA decay

(2012) Zsuzsanna Mérai et al.   PLANT JOURNAL

A Role for Nonsense-Mediated mRNA Decay in Plants: Pathogen Responses Are Induced in Arabidopsis thaliana NMD Mutants

(2012) Samantha Rayson et al.   PLoS One

Structural Basis of the PNRC2-Mediated Link between mRNA Surveillance and Decapping

(2012) Tingfeng Lai et al.   STRUCTURE

Conserved Peptide Upstream Open Reading Frames are Associated with Regulatory Genes in Angiosperms

(2012) Richard A. Jorgensen et al.   Frontiers in Plant Science

Rooting the Eukaryotic Tree with Mitochondrial and Bacterial Proteins

(2011) R. Derelle et al.   MOLECULAR BIOLOGY AND EVOLUTION

RNA Homeostasis Governed by Cell Type-Specific and Branched Feedback Loops Acting on NMD

(2011) Lulu Huang et al.   MOLECULAR CELL

Identification of a MicroRNA that Activates Gene Expression by Repressing Nonsense-Mediated RNA Decay

(2011) Ivone G. Bruno et al.   MOLECULAR CELL

The Arabidopsis lyrata genome sequence and the basis of rapid genome size change

(2011) Tina T Hu et al.   NATURE GENETICS

Gene silencing by microRNAs: contributions of translational repression and mRNA decay

(2011) Eric Huntzinger et al.   NATURE REVIEWS GENETICS

Repairing breaks in the plant genome: the importance of keeping it together

(2011) Wanda M. Waterworth et al.   NEW PHYTOLOGIST

N- and C-terminal Upf1 phosphorylations create binding platforms for SMG-6 and SMG-5:SMG-7 during NMD

(2011) Yukiko Okada-Katsuhata et al.   NUCLEIC ACIDS RESEARCH

SMART 7: recent updates to the protein domain annotation resource

(2011) I. Letunic et al.   NUCLEIC ACIDS RESEARCH

Alternative splicing and nonsense-mediated decay modulate expression of important regulatory genes in Arabidopsis

(2011) Maria Kalyna et al.   NUCLEIC ACIDS RESEARCH

Nonsense-Mediated mRNA Decay Factors, UPF1 and UPF3, Contribute to Plant Defense

(2011) Hee-Jeong Jeong et al.   PLANT AND CELL PHYSIOLOGY

Functional analysis of the grapevine paralogs of the SMG7 NMD factor using a heterolog VIGS-based gene depletion-complementation system

(2011) Anna Hangyáné Benkovics et al.   PLANT MOLECULAR BIOLOGY

Is There a Classical Nonsense-Mediated Decay Pathway in Trypanosomes?

(2011) Praveen Delhi et al.   PLoS One

Autoregulation of the nonsense-mediated mRNA decay pathway in human cells

(2011) H. Yepiskoposyan et al.   RNA

Transcriptional Control of Gene Expression by MicroRNAs

(2010) Basel Khraiwesh et al.   CELL

Polypyrimidine tract-binding protein homologues from Arabidopsis underlie regulatory circuits based on alternative splicing and downstream control

(2010) Eva Stauffer et al.   PLANT JOURNAL

Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay

(2010) D. R. McIlwain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AAA+ Proteins RUVBL1 and RUVBL2 Coordinate PIKK Activity and Function in Nonsense-Mediated mRNA Decay

(2010) N. Izumi et al.   Science Signaling

Small RNAs and Their Roles in Plant Development

(2009) Xuemei Chen   Annual Review of Cell and Developmental Biology

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

Emerging common themes in regulation of PIKKs and PI3Ks

(2009) Harri Lempiäinen et al.   EMBO JOURNAL

Nonsense-Mediated mRNA Decay Effectors Are Essential for Zebrafish Embryonic Development and Survival

(2009) N. Wittkopp et al.   MOLECULAR AND CELLULAR BIOLOGY

Human Proline-Rich Nuclear Receptor Coregulatory Protein 2 Mediates an Interaction between mRNA Surveillance Machinery and Decapping Complex

(2009) Hana Cho et al.   MOLECULAR CELL

Extensive coupling of alternative splicing of pre-mRNAs of serine/arginine (SR) genes with nonsense-mediated decay

(2009) Saiprasad G. Palusa et al.   NEW PHYTOLOGIST

The upstream open reading frame of the Arabidopsis AtMHX gene has a strong impact on transcript accumulation through the nonsense-mediated mRNA decay pathway

(2009) Helen Saul et al.   PLANT JOURNAL

Plant upstream ORFs can trigger nonsense-mediated mRNA decay in a size-dependent manner

(2009) Tünde Nyikó et al.   PLANT MOLECULAR BIOLOGY

High resolution transcriptome maps for wild-type and nonsense-mediated decay-defective Caenorhabditis elegans

(2009) Arun K Ramani et al.   GENOME BIOLOGY

Recognition and elimination of nonsense mRNA

(2008) O MUHLEMANN et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Conserved upstream open reading frames in higher plants

(2008) Michael K Tran et al.   BMC GENOMICS

Kill the messenger: mRNA decay and plant development

(2008) Dmitry A Belostotsky et al.   CURRENT OPINION IN PLANT BIOLOGY

Inter-kingdom conservation of mechanism of nonsense-mediated mRNA decay

(2008) Zoltán Kerényi et al.   EMBO JOURNAL

Incomplete nonsense-mediated mRNA decay in Giardia lamblia

(2008) Y CHEN et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Arabidopsis SMG7 protein is required for exit from meiosis

(2008) N. Riehs et al.   JOURNAL OF CELL SCIENCE

Regulation of Multiple Core Spliceosomal Proteins by Alternative Splicing-Coupled Nonsense-Mediated mRNA Decay

(2008) A. L. Saltzman et al.   MOLECULAR AND CELLULAR BIOLOGY

SMG6 promotes endonucleolytic cleavage of nonsense mRNA in human cells

(2008) Andrea B Eberle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan

(2008) E. Huntzinger et al.   RNA