Article
Agronomy
Langlang Ma, Chen Wang, Yu Hu, Wei Dai, Zhenjuan Liang, Chaoying Zou, Guangtang Pan, Thomas Lubberstedt, Yaou Shen
Summary: The key gene MADS26 affecting maize seed germination was identified through GWAS and transcriptomics. The study revealed variations within MADS26 that regulate seed germination traits and showed that overexpressing MADS26 improves seed germination in Arabidopsis. Understanding the genetic control of seed germination ability in maize is important for improving maize yield.
THEORETICAL AND APPLIED GENETICS
(2022)
Article
Biochemistry & Molecular Biology
Yunlong Wang, Yihua Wang, Xiaopin Zhu, Yulong Ren, Hui Dong, Erchao Duan, Xuan Teng, Huanhuan Zhao, Rongbo Chen, Xiaoli Chen, Jie Lei, Hang Yang, Yunlu Tian, Liangming Chen, Xi Liu, Shijia Liu, Ling Jiang, Haiyang Wang, Jianmin Wan
Summary: This study investigates the effects of tetrapyrrole biosynthesis-related GUN mutants on nuclear and plastid gene expression in rice. The results show that the TPB-related GUN genes control retrograde plastid signaling by regulating the expression of plastid-encoded genes.
PLANT COMMUNICATIONS
(2023)
Article
Biochemistry & Molecular Biology
Danesh H. Sopariwala, Neah Likhite, Gungsheng Pei, Fnu Haroon, Lisa Lin, Vikas Yadav, Zhongming Zhao, Vihang A. Narkar
Summary: ERR alpha is induced in skeletal muscle by hindlimb ischemia or hypoxia, and its overexpression can drive a switch in myofiber type and activate gene programs related to angiogenesis in muscle. This leads to increased baseline capillarity and arterioles, as well as improved perfusion recovery in ischemic muscle, suggesting ERR alpha as a potential target for treating PAD/CLI.
Article
Biochemistry & Molecular Biology
Mariam Sahrawy, Juan Fernandez-Trijueque, Paola Vargas, Antonio J. Serrato
Summary: This study investigates the localization and function of Thioredoxins f and m in Arabidopsis. The results reveal different localization patterns of these proteins within chloroplasts and their presence in non-photosynthetic plastids and roots. Furthermore, the study suggests that TRXm2 might activate cFBP1 in root plastids.
Article
Multidisciplinary Sciences
Xueguang Zhang, Lingbo Wang, Yongyi Ma, Yan Wang, Hongqian Liu, Mohan Liu, Lang Qin, Jinghong Li, Chuan Jiang, Xiaojian Zhang, Xudong Shan, Yuliang Liu, Jinsong Li, Yaqian Li, Rui Zheng, Yongkang Sun, Jianfeng Sun, Xiangyou Leng, Yan Liang, Feng Zhang, Xiaohui Jiang, Yihong Yang, Ying Shen
Summary: CEP128 plays a crucial role in male fertility, and its variation can lead to reduced sperm counts and abnormal morphology, thus affecting male reproductive function. Furthermore, CEP128 is important for the regulation of ciliogenesis in the testes.
NATURE COMMUNICATIONS
(2022)
Article
Biochemistry & Molecular Biology
Zhao Li, Kaikai Mao, Ruoheng Jin, Tingwei Cai, Yao Qin, Yunhua Zhang, Shun He, Kangsheng Ma, Hu Wan, Xuexiang Ren, Jianhong Li
Summary: The study found that miRNA novel_268 is involved in the resistance of Nilaparvata lugens to nitenpyram and clothianidin by targeting the ABC transporter NlABCG3. These results provide more insights into the transcriptional regulation of ABC transporters in the insecticide resistance of N. lugens.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Review
Plant Sciences
Variyata Agrawal, Vijetna Singh, Bhumi Nath Tripathi
Summary: Retrograde signaling refers to the transfer of signals from semi-autonomous cell organelles to the nucleus to regulate gene expression. Chloroplasts, which are highly sensitive to environmental stimuli, generate retrograde signals and transport them to the nucleus through the cytosol to adjust gene expression in response to environmental fluctuations. While progress has been made in understanding retrograde signaling, the mechanisms responsible for transmitting signals from chloroplast to nucleus are still unclear. This review highlights the strategies used to detect retrograde signals and their implications for cellular processes under stress conditions.
PHYSIOLOGIA PLANTARUM
(2023)
Article
Biochemistry & Molecular Biology
Sabrina De Brasi-Velasco, Antonio Sanchez-Guerrero, Mari -Cruz Castillo, Didier Vertommen, Jose Leon, Francisca Sevilla, Ana Jimenez
Summary: Abscisic acid (ABA) plays a crucial role in plant growth and development, and its signaling is regulated by the nuclear receptor PYR1 and the protein TRXo1 through redox regulation. PYR1 inhibits the activity of phosphatase PP2Cs, while TRXo1 reduces oxidized PYR1 and restores its inhibitory function. This study reveals a previously unknown redox regulation of TRXo1 on PYR1, which may be important for ABA signaling.
Article
Biotechnology & Applied Microbiology
Rabea Ghandour, Yang Gao, Josephin Laskowski, Rouhollah Barahimipour, Stephanie Ruf, Ralph Bock, Reimo Zoschke
Summary: In plant biotechnology, the expression of transgenes in chloroplasts is common practice. However, the potential unintended effects on native chloroplast genes are often overlooked. This study examined the expression of the chloroplast genome in transplastomic tobacco plants and found that transgene insertion can lead to overexpression of downstream genes and interfere with the transcription and translation of nearby genes. The study suggests strategies to minimize unintended consequences of transgene expression on native chloroplast genes.
PLANT BIOTECHNOLOGY JOURNAL
(2023)
Article
Multidisciplinary Sciences
Shoko Fujino, Sayuri Hamano, Atsushi Tomokiyo, Risa Sugiura, Daiki Yamashita, Daigaku Hasegawa, Hideki Sugii, Shinsuke Fujii, Tomohiro Itoyama, Hirofumi Miyaji, Hidefumi Maeda
Summary: Conventional direct pulp-capping materials induce odontoblastic differentiation of dental pulp stem cells and promote reparative dentin formation, but sometimes result in dentin with poor sealing properties. This study explored the role of dopamine (DA) in odontoblastic differentiation and reparative dentin formation. The results showed that DA, produced by tyrosine hydroxylase (TH), plays a role in odontoblastic differentiation and induces the formation of tubular reparative dentin. These findings could contribute to the development of therapies for preserving vital pulp tissues.
SCIENTIFIC REPORTS
(2023)
Article
Agronomy
Qiuyan Ren, Hua Jiang, Wenyang Xiang, Yang Nie, Song Xue, Haijian Zhi, Kai Li, Junyi Gai
Summary: This study cloned the resistance gene GmCAL against Soybean mosaic virus and found that it plays a crucial regulatory role in soybean resistance.
Article
Plant Sciences
Xueling Li, Yudou Cheng, Ying Wang, Xiaohe Yang, Chuangqi Wei, Junfeng Guan
Summary: This study investigated the effects of storage temperature and treatment method on anthocyanin accumulation and ethylene signal pathway in plum fruit. The results showed that fruits stored at 10℃ had higher ethylene production rate and more anthocyanin in the flesh. Exogenous ethylene treatment increased anthocyanin accumulation, while 1-MCP treatment inhibited anthocyanin accumulation.
Article
Microbiology
Binbin Lu, Meng Liu, Liang Gu, Ying Li, Shijun Shen, Gangqiang Guo, Fei Wang, Xiaohui He, Yuemeng Zhao, Xiaomin Shang, Liping Wang, Guang Yang, Qianshu Zhu, Jun Cao, Cizhong Jiang, Richard Culleton, Gang Wei, Qingfeng Zhang
Summary: The study identifies HMGB1 as a critical architectural factor in the high-order genome organization and gene expression regulation in the malaria parasite Plasmodium falciparum. Loss of HMGB1 disrupts chromosome organization and leads to dysregulated gene expression, particularly silencing of the primary virulence genes. The reconstitution of nuclear organization by complementation of HMGB1 rescues the exclusive expression of the virulence gene family, indicating HMGB1 as a potential target for antimalarial strategies.
Article
Cell Biology
Keita Yamamoto, Susumu Goyama, Shuhei Asada, Takeshi Fujino, Taishi Yonezawa, Naru Sato, Reina Takeda, Akiho Tsuchiya, Tomofusa Fukuyama, Yosuke Tanaka, Akihiko Yokoyama, Hikaru Toya, Ayana Kon, Yasuhito Nannya, Rena Onoguchi-Mizutani, Shinichi Nakagawa, Tetsuro Hirose, Seishi Ogawa, Nobuyoshi Akimitsu, Toshio Kitamura
Summary: The study reveals that ASXL1 plays a role in the formation of paraspeckles, and a pathogenic ASXL1-MT mutation can disrupt paraspeckles and reduce the interactions between non-coding RNA NEAT1 and protein NONO.
Article
Agronomy
Shuang Song, Ying Wang, Xin Ding, Yunlu Tian, Zewan Wu, Hang Li, Qing Li, Yunpeng Wang, Shirong Zhou, Xiaoou Dong, Jianmin Wan, Linglong Liu
Summary: In rice, plastid-encoded RNA polymerase (PEP) regulates chloroplast genes involved in photosynthesis and chloroplast development. The PEP-associated protein (PAP) PAP7/pTAC14 is essential for PEP complex formation, but its role in rice chloroplast development is unclear. This study identified the w81 mutant with yellow-green leaves before the four-leaf stage, reduced chlorophyll content, abnormal chloroplast structure, and elevated reactive oxygen species (ROS) level. Map-based cloning revealed a mutation in the PAP7 gene causing abnormal splicing and longer transcripts. The OsPAP7 protein localizes to the chloroplast and interacts with OsPAP5, highlighting its crucial role in chloroplast development in rice.
