Red human hair pheomelanin is a potent pro-oxidant mediating UV-independent contributory mechanisms of melanomagenesis

How does pheomelanin synthesis contribute to melanomagenesis?

(2013) Ann M. Morgan et al.   BIOESSAYS

New research on melanoma risk in red-haired people

(2013) Carrie Printz   CANCER

Being in the red: a no-win situation with melanoma

(2013) Zalfa A. Abdel-Malek et al.   Pigment Cell & Melanoma Research

Melanins and melanogenesis: methods, standards, protocols

(2013) Marco d'Ischia et al.   Pigment Cell & Melanoma Research

Red Hair Benzothiazines and Benzothiazoles: Mutation-Inspired Chemistry in the Quest for Functionality

(2012) Alessandra Napolitano et al.   ACCOUNTS OF CHEMICAL RESEARCH

Probing the Motional Behavior of Eumelanin and Pheomelanin with Solid-State NMR Spectroscopy: New Insights into the Pigment Properties

(2012) Pierre Thureau et al.   CHEMISTRY-A EUROPEAN JOURNAL

Novel properties of melanins include promotion of DNA strand breaks, impairment of repair, and reduced ability to damage DNA after quenching of singlet oxygen

(2012) Andréia Akemi Suzukawa et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Eumelanin Intermediate 5,6-Dihydroxyindole-2-Carboxylic Acid Is a Messenger in the Cross-Talk among Epidermal Cells

(2012) Daniela Kovacs et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Time-dependent reactive species formation and oxidative stress damage in the skin after UVB irradiation

(2012) V.A. Terra et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Alpha-Melanocyte–Stimulating Hormone Suppresses Oxidative Stress through a p53-Mediated Signaling Pathway in Human Melanocytes

(2012) Ana Luisa Kadekaro et al.   MOLECULAR CANCER RESEARCH

An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background

(2012) Devarati Mitra et al.   NATURE

An Endogenous Electron Spin Resonance (ESR) Signal Discriminates Nevi from Melanomas in Human Specimens: A Step Forward in Its Diagnostic Application

(2012) Eleonora Cesareo et al.   PLoS One

Melanoma induction by ultraviolet A but not ultraviolet B radiation requires melanin pigment

(2012) Frances P. Noonan et al.   Nature Communications

A melanin-inspired pro-oxidant system for dopa(mine) polymerization: mimicking the natural casing process

(2011) Giorgia Greco et al.   CHEMICAL COMMUNICATIONS

Increased cysteinyldopa plasma levels hint to melanocyte as stress sensor in psoriasis

(2011) Lucia Panzella et al.   EXPERIMENTAL DERMATOLOGY

Uncovering the Structure of Human Red Hair Pheomelanin: Benzothiazolylthiazinodihydroisoquinolines As Key Building Blocks

(2011) Giorgia Greco et al.   JOURNAL OF NATURAL PRODUCTS

Diversity of human hair pigmentation as studied by chemical analysis of eumelanin and pheomelanin

(2011) S. Ito et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

The fundamental building blocks of red human hair pheomelanin are isoquinoline-containing dimers

(2011) Giorgia Greco et al.   Pigment Cell & Melanoma Research

ESR study of photoinduced free radicals by visible light in hair and the effects of ascorbic acid (vitamin C)

(2011) E. Chikvaidze et al.   INTERNATIONAL JOURNAL OF COSMETIC SCIENCE

Zinc-induced Structural Effects Enhance Oxygen Consumption and Superoxide Generation in Synthetic Pheomelanins on UVA/Visible Light Irradiation†

(2010) Lucia Panzella et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Is DHICA the key to dopachrome tautomerase and melanocyte functions?

(2010) Lucia Panzella et al.   Pigment Cell & Melanoma Research

Human Iridal Stroma Melanosomes of Varying Pheomelanin Contents Possess a Common Eumelanic Outer Surface

(2009) Dana N. Peles et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Isomeric cysteinyldopas provide a (photo)degradable bulk component and a robust structural element in red human hair pheomelanin

(2009) Giorgia Greco et al.   Pigment Cell & Melanoma Research

The "Benzothiazine" Chromophore of Pheomelanins: A Reassessment

(2007) Alessandra Napolitano et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Chemistry of Mixed Melanogenesis—Pivotal Roles of Dopaquinone

(2007) Shosuke Ito et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY