Brain metastasis is predetermined in early stages of cutaneous melanoma by CD44v6 expression through epigenetic regulation of the spliceosome

Endogenous Damage-Associated Molecular Pattern Molecules at the Crossroads of Inflammation and Cancer

(2015) Geetha Srikrishna et al.   NEOPLASIA

Cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

DNA methylation and gene deletion analysis of brain metastases in melanoma patients identifies mutually exclusive molecular alterations

(2014) D. M. Marzese et al.   NEURO-ONCOLOGY

Automated Tracking of Nanoparticle-labeled Melanoma Cells Improves the Predictive Power of a Brain Metastasis Model

(2013) T. Sundstrom et al.   CANCER RESEARCH

Epigenome-wide DNA methylation landscape of melanoma progression to brain metastasis reveals aberrations on homeobox D cluster associated with prognosis

(2013) Diego M. Marzese et al.   HUMAN MOLECULAR GENETICS

Demonstration of a Melanoma-Specific CD44 Alternative Splicing Pattern That Remains Qualitatively Stable, but Shows Quantitative Changes during Tumour Progression

(2013) Livia Raso-Barnett et al.   PLoS One

Epigenetic Regulation of Cancer Stem Cell Genes in Triple-Negative Breast Cancer

(2012) Naofumi Kagara et al.   AMERICAN JOURNAL OF PATHOLOGY

Snail Represses the Splicing Regulator Epithelial Splicing Regulatory Protein 1 to Promote Epithelial-Mesenchymal Transition

(2012) Lauren M. Reinke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-Wide Determination of a Broad ESRP-Regulated Posttranscriptional Network by High-Throughput Sequencing

(2012) K. A. Dittmar et al.   MOLECULAR AND CELLULAR BIOLOGY

The effect of stroke on immune function

(2012) Roberta Brambilla et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell

(2012) Toshifumi Yae et al.   Nature Communications

Assessment of Prognostic Circulating Tumor Cells in a Phase III Trial of Adjuvant Immunotherapy After Complete Resection of Stage IV Melanoma

(2011) Sojun Hoshimoto et al.   ANNALS OF SURGERY

Elucidating the mechanobiology of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform

(2011) Badriprasad Ananthanarayanan et al.   BIOMATERIALS

Downregulation of microRNA-29c is associated with hypermethylation of tumor-related genes and disease outcome in cutaneous melanoma

(2011) Tung Nguyen et al.   Epigenetics

Hyaluronan-CD44 interactions as potential targets for cancer therapy

(2011) Suniti Misra et al.   FEBS Journal

Regulation of alternative splicing by the core spliceosomal machinery

(2011) A. L. Saltzman et al.   GENES & DEVELOPMENT

The metastatic microenvironment: Brain-residing melanoma metastasis and dormant micrometastasis

(2011) Sivan Izraely et al.   INTERNATIONAL JOURNAL OF CANCER

CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression

(2011) Rhonda L. Brown et al.   JOURNAL OF CLINICAL INVESTIGATION

Combined treatment of the immunoconjugate bivatuzumab mertansine and fractionated irradiation improves local tumour control in vivo

(2011) Kristin Gurtner et al.   RADIOTHERAPY AND ONCOLOGY

Serial Monitoring of Circulating Tumor Cells Predicts Outcome of Induction Biochemotherapy plus Maintenance Biotherapy for Metastatic Melanoma

(2010) K. Koyanagi et al.   CLINICAL CANCER RESEARCH

CD44, a therapeutic target for metastasising tumours

(2010) Véronique Orian-Rousseau   EUROPEAN JOURNAL OF CANCER

The brain microenvironment and cancer metastasis

(2010) Isaiah J. Fidler et al.   MOLECULES AND CELLS

The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events

(2010) Claude C. Warzecha et al.   RNA Biology

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

CpG Island Methylator Phenotype Predicts Progression of Malignant Melanoma

(2009) A. Tanemura et al.   CLINICAL CANCER RESEARCH

Final Version of 2009 AJCC Melanoma Staging and Classification

(2009) Charles M. Balch et al.   JOURNAL OF CLINICAL ONCOLOGY

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Phase I trial with the CD44v6-targeting immunoconjugate bivatuzumab mertansine in head and neck squamous cell carcinoma

(2008) Herbert Riechelmann et al.   ORAL ONCOLOGY