Advances in the synthesis and pharmacological activity of lupane-type triterpenoid saponins

Haemolytic activity, cytotoxicity and membrane cell permeabilization of semi-synthetic and natural lupane- and oleanane-type saponins

(2009) Charles Gauthier et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis, cytotoxicity, and haemolytic activity of chacotrioside lupane-type neosaponins and their germanicane-type rearrangement products

(2009) Charles Gauthier et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Lupeol, a novel anti-inflammatory and anti-cancer dietary triterpene

(2009) Mohammad Saleem   CANCER LETTERS

Current Synthesis of Triterpene Saponins

(2009) Biao Yu et al.   Chemistry-An Asian Journal

Recent Progress in the Synthesis of Naturally Occurring Triterpenoid Saponins

(2009) Charles Gauthier et al.   MINI-REVIEWS IN ORGANIC CHEMISTRY

Betulin Is a Potent Anti-Tumor Agent that Is Enhanced by Cholesterol

(2009) Franziska B. Mullauer et al.   PLoS One

Lupeol: Connotations for chemoprevention

(2008) Pranav K. Chaturvedi et al.   CANCER LETTERS

Synthesis of lupane-type saponins bearing mannosyl and 3,6-branched trimannosyl residues and their evaluation as anticancer agents

(2008) Piotr Cmoch et al.   CARBOHYDRATE RESEARCH

Synthesis and Cytotoxicity of Bidesmosidic Betulin and Betulinic Acid Saponins

(2008) Charles Gauthier et al.   JOURNAL OF NATURAL PRODUCTS

Saponins in Tumor Therapy

(2008) Christopher Bachran et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Anti-Cancer Effect of Betulin on a Human Lung Cancer Cell Line: A Pharmacoproteomic Approach Using 2 D SDS PAGE Coupled with Nano-HPLC Tandem Mass Spectrometry

(2008) Jae Pyo et al.   PLANTA MEDICA

Synthesis of two natural betulinic acid saponins containing α-l-rhamnopyranosyl-(1→2)-α-l-arabinopyranose and their analogues

(2008) Charles Gauthier et al.   TETRAHEDRON

Synthesis of betulinic acid acyl glucuronide for application in anticancer prodrug monotherapy

(2008) Charles Gauthier et al.   TETRAHEDRON LETTERS