4.3 Article

A dimeric chromanone and a phthalide: Metabolites from the seagrass-derived fungus Bipolaris sp PSU-ES64

Journal

PHYTOCHEMISTRY LETTERS
Volume 5, Issue 3, Pages 604-608

Publisher

ELSEVIER
DOI: 10.1016/j.phytol.2012.06.004

Keywords

Dimeric chromanone; Phthalide; Seagrass-derived fungus; Bipolaris sp.; Antioxidant; Antimicrobial

Funding

  1. Thailand Research Fund [RTA5480002]
  2. Development and Promotion of Science and Technology Talents Project for a scholarship
  3. Center of Excellence for Innovation in Chemistry (PERCH-CIC)
  4. Prince of Songkla University

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Two new metabolites, a dimeric chromanone, bipolarinone (1), and a phthalide, bipolarilide (2), as well as eight known compounds have been isolated from the seagrass-derived fungus Bipolaris sp. PSU-ES64. The structures were elucidated by analysis of spectroscopic data. The absolute configuration of 1 was determined by circular dichroism spectroscopy, Mosher's method, and NOEDIFF data. The antioxidant and antimicrobial activities of the isolated compounds were examined. (C) 2012 Phytochemical Society of Europe. Published by Elsevier B. V. All rights reserved.

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