Journal
PHYTOCHEMISTRY LETTERS
Volume 5, Issue 2, Pages 313-315Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.phytol.2012.02.009
Keywords
Artemisia anomala; Eudesmane sesquiterpenoids; Cytotoxicity
Categories
Funding
- National Natural Science Foundation of China [30973629]
- China Postdoctoral Science Foundation [20110490251]
Ask authors/readers for more resources
Two new eudesmane sesquiterpenoids artanoate (1) and eudesmanomolide (2) were isolated from the aerial parts of Artemisia anomala S. Moore. Their structures were elucidated as methyl (4R, 5S, 6S, 7S, 10R)-1-oxo-4, 6-dihydroxy-eudesma-2, 11 (13)-dien-12-oate (1) and (1R, 5R, 6R, 10R)-3, 13-diacetoxy-1-hydroxy-3, 7(11)-diene-12, 6-olide (2) on the basis of extensive spectroscopic analyses. Compound 1 showed cytotoxicity against HCT-8 cell lines with IC50 value of 9.13 mu M, and compound 2 exhibited inhibitory activities against HCT-8 and A549 cell lines with IC50 values of 3.76 and 5.49 mu M, respectively. (C) 2012 Phytochemical Society of Europe. Published by Elsevier B. V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available