Journal
PHYTOCHEMISTRY
Volume 72, Issue 14-15, Pages 1826-1832Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.phytochem.2011.05.010
Keywords
Toussaintia orientalis; Annonaceae; Toussaintines; Indolidinoids; Hydrobenzofuranoid; Antimicrobial
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Funding
- Sida/SAREC
- Natural Pesticides Research Project
- German Academic Exchange Services (DAAD)
- NAPRECA under DAAD/NAPRECA
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Toussaintine A (N-cinnamoyl-5,6-dehydro-4-hydroxyindolidin-2,7-dione), toussaintine B (N-cinnamoyl-5,6-dehydro-4,7-dihydroxyindolidin-2-one), toussaintine C (N-cinnamoyl-5,6-dehydro-4-hydroxyindolidin-7-one), toussaintine D (N-cinnamoyl-2-amino-4-hydroxy-7-oxo-2,3,8,9-tetrahydrobenzofuran) and toussaintine E (N-cinnamoyl-1-acetoxymethyl-2-amino-1-hydroxycyclox-5-en-4-one) were isolated as antibacterial and antifungal constituents of the leaves of Toussaintia orientalis Verdc. (Annonaceae) and their structures established from analysis of spectroscopic data. The compounds belong to a series of variously cyclized aminocinnamoyl tetraketide derivatives, showing the importance of rarely occurring Annonaceae species as sources of structurally diverse natural products. (C) 2011 Elsevier Ltd. All rights reserved.
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