Article
Fisheries
Asma W. Al-Thomali, Hend M. Tag, Amaal Mohammadein, Nahla S. El-Shenawy, Mohamed Salah El-Naggar
Summary: The study revealed that exposure to mercaptophos had negative effects on the endocrine system and liver tissue of Cyprinus carpio, leading to exacerbated oxidative stress reactions, alterations in hormone levels, and pathological changes in liver and pancreatic cells.
AQUACULTURE REPORTS
(2022)
Article
Fisheries
Artem V. Nedoluzhko, Maria V. Gladysheva-Azgari, Gulmira M. Shalgimbayeva, Alexander A. Volkov, Natalia V. Slobodova, Svetlana V. Tsygankova, Eugenia S. Boulygina, Van Q. Nguyen, The T. Pham, Duc T. Nguyen, Fedor S. Sharko, Sergey M. Rastorguev
Summary: The study used ddRAD-seq to assess the genetic impact of aquaculture carps on wild common carp populations in northern Vietnam. The research revealed that some wild carp populations have a significant contribution to farmed fish ancestry, with pure aquaculture specimens being quite rare in wild habitats.
Article
Fisheries
Vojtech Kaspar, Martin Hubalek, Martin Psenicka, Katsutoshi Arai, John B. Taggart, Roman Franek
Summary: Methods of induction of uniparental inheritance have been developed for model organisms as well as for species of commercial interest, with cold-shock androgenesis showing promise in successfully inducing haploid progeny in common carp. Compared to other techniques, cold-shock androgenesis was found to be effective in common carp, providing a new possibility for isogenic line production.
Article
Environmental Sciences
Christoph Steinbach, Ilka Lutz, Marie Sandova, Michal Pech, Eva Salkova, Adam Borik, Olga Valentova, Hana Kocour Kroupova
Summary: The objective of this study was to assess the effects of the synthetic progestin levonorgestrel (LNG) on early development and the thyroid system of carp. The results showed that LNG had no significant effect on early development or the occurrence of morphological anomalies in carp. There were no pathological alterations in the thyroid follicles. However, mRNA expression analysis revealed differential effects of LNG treatment on iodothyronine deiodinases (dio1, 2, 3) during carp development, indicating possible hypothyroidism. Moreover, LNG caused parallel changes in the hypothalamus-pituitary-thyroid and hypothalamus-pituitary-gonad axes.
Article
Fisheries
Mei Wang, Lin Chen, Zhixiong Zhou, Junzhu Xiao, Baohua Chen, Peihong Huang, Chengyu Li, Yaguo Xue, Ruoting Liu, Yulin Bai, Mengzhen Yan, Shuimu Hu, Yinru Dai, Chenyu Yang, Xiaoqing Zou, Zou Jiang, Jianxin Feng, Tao Zhou, Peng Xu
Summary: The present study provides insights into the genetic network and underlying mechanisms of early sex determination and gonadal differentiation in C. carpo. Differential expression genes related to sex differentiation and gonadal development were identified, and key time periods for sex determination and differentiation were determined. Functional enrichment analysis and protein-protein interaction analysis further revealed the role of these genes in sex differentiation and gonadal development. The study also showed sexual dimorphism in plasma 17 beta-estradiol and 11-Keto-testosterone levels in C. carpo.
Article
Environmental Sciences
Yuanyuan Zhang, Di Wu, Ze Fan, Jinnan Li, Lei Gao, Yu'e Wang, Liansheng Wang
Summary: Previous studies have shown that MC-LR enters intestinal tissues through organic anion-transporting polypeptides, resulting in ferroptosis-related damage including ER stress, iron accumulation, and changes in glutathione levels. The GSH/GPx 4 pathway plays a significant role in response to MC-LR exposure.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Environmental Sciences
Maurizio Manera, Giuseppe Castaldelli, Luisa Giari
Summary: Carp kidney can be used to assess the thyroid disrupting potential of PFOA. The study found that exposure to PFOA increased the abundance of thyroid follicles and caused vesiculation in carp. The structure and ultrastructure of thyroid follicles were also affected. These results suggest that fish kidney could serve as a multipurpose biomarker organ for environmental pathology research.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Multidisciplinary Sciences
Juntao Li, Haixiao Liu, Zhong Xiao, Xian Wei, Zhe Liu, Zhipeng Zhang
Summary: Chinese carps, which are of great economic importance in China, have seen a significant decline in population due to the construction of barrages. The study of carp's swimming performance is crucial for the design of fishways to protect fish resources.
Article
Fisheries
Seyyed Morteza Hoseini, Nava Majidiyan, Ali Taheri Mirghaed, Seyed Hossein Hoseinifar, Hien Van Doan
Summary: Fish transportation is a stressful process for fish in the aquaculture industry. The present study shows that dietary supplementation of glycine can improve the antioxidant capacity and reduce stress in common carp during transportation.
Article
Fisheries
David Waikhom, Jeena Kezhedath, Rahul Krishnan, Tincy Varghese, Pani Prasad Kurcheti, Rajendran Kooloth Valappil
Summary: This study evaluated the induction of trained immunity markers in common carp using ll-glucan and revealed the metabolic basis and epigenetic modifications of trained immunity induced by ll-glucan. The study also confirmed the increased metabolic activity and expression profiles of proinflammatory cytokines in cells stimulated with ll-glucan. These findings further support the importance of trained immunity in fish and provide genomic evidence.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Multidisciplinary Sciences
Alena Honzlova, Helena Curdova, Lenka Schebestova, Pavel Bartak, Alzbeta Stara, Josef Priborsky, Anna Koubova, Zdenka Svobodova, Josef Velisek
Summary: This study aimed to determine nitrogen factors for farmed common carp, which can help ensure consumers are purchasing correctly labelled products.
SCIENTIFIC REPORTS
(2021)
Article
Veterinary Sciences
Yidan Xu, Yaqin Jiao, Jian Yang, Aijuan Tan, Deyuan Ou, Xuqin Song, Shiming Lv
Summary: In this study, a high-performance liquid chromatography method was used to analyze the pharmacokinetic profile and residue depletion of eugenol in carp tissues and plasma. The results showed good linearity, accuracy, and sensitivity of the developed method. The recommended concentration of 35 mg/L eugenol as an anesthetic in carp was found to have favorable effects and no mortality. This study is important for establishing MRL regulations and setting withdrawal periods.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Biodiversity Conservation
I. G. Stuart, B. G. Fanson, J. P. Lyon, J. Stocks, S. Brooks, A. Norris, L. Thwaites, M. Beitzel, M. Hutchison, Q. Ye, J. D. Koehn, A. F. Bennett
Summary: Research on carp populations in Australia provides vital information for control measures, with the eastern region of Australia being the key distribution area, making control measures crucial.
BIOLOGICAL CONSERVATION
(2021)
Article
Environmental Sciences
Sib Sankar Giri, Min Jung Kim, Sang Guen Kim, Sang Wha Kim, Jeong Woo Kang, Jun Kwon, Sung Bin Lee, Won Joon Jung, Venkatachalam Sukumaran, Se Chang Park
Summary: Curcumin, a compound found in turmeric, has been shown to have antioxidant, anti-inflammatory, and immunostimulatory effects in fish. This study demonstrated that dietary supplementation of curcumin can protect fish against lead-induced toxicity by reducing lead accumulation, improving survival rates, reversing biochemical parameter changes, and enhancing immune responses.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Engineering, Multidisciplinary
Gang Zhai, Tingting Shu, Kuangxin Chen, Qiyong Lou, Jingyi Jia, Jianfei Huang, Chuang Shi, Xia Jin, Jiangyan He, Donghuo Jiang, Xueqiao Qian, Wei Hu, Zhan Yin
Summary: This research demonstrates a novel strategy for producing a monosex fish population with the advantages of sexual dimorphism in growth through genetic manipulation targeting a single locus, providing new opportunities for the aquaculture industry.
Article
Biochemistry & Molecular Biology
Stefan de Gelder, Henrik Sundh, Thamar N. M. Pelgrim, Josef D. Rasinger, Lotte van Daal, Gert Flik, Marc H. G. Berntssen, Peter H. M. Klaren
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2018)
Article
Multidisciplinary Sciences
Bilge San, Julien Rougeot, Kai Voeltzke, Gertie van Vegchel, Marco Aben, Karolina M. Andralojc, Gert Flik, Leonie M. Kamminga
Article
Behavioral Sciences
Ruud van den Bos, Joep Althuizen, Katharina Tschigg, Maud Bomert, Jan Zethof, Gert Filk, Marnix Gorissen
BEHAVIOURAL PHARMACOLOGY
(2019)
Article
Education & Educational Research
Wiljan J. A. J. Hendriks, Nicole Bakker, Helma Pluk, Arjan de Brouwer, Be Wieringa, Alessandra Cambi, Mirjam Zegers, Derick G. Wansink, Ron Leunissen, Peter H. M. Klaren
BMC MEDICAL EDUCATION
(2019)
Article
Immunology
Stephanie C. M. van Dalen, Arjen B. Blom, Birgitte Walgreen, Annet W. Sloetjes, Monique M. A. Helsen, Edwin J. W. Geven, Menno ter Huurne, Thomas Vogl, Johannes Roth, Fons A. J. van de Loo, Marije Koenders, Louis Casteille, Peter M. van der Kraan, Martijn H. J. van den Bosch, Peter L. E. M. van Lent
FRONTIERS IN IMMUNOLOGY
(2019)
Article
Biology
Luis Vargas-Chacoff, Francisco J. Arjona, Ignacio Ruiz-Jarabo, Angel Garcia-Lopez, Gert Flik, Juan M. Mancera
JOURNAL OF THERMAL BIOLOGY
(2020)
Article
Multidisciplinary Sciences
Iris L. E. van de Pol, Gert Flik, Wilco C. E. P. Verberk
Article
Immunology
Ruud van den Bos, Suzanne Cromwijk, Katharina Tschigg, Joep Althuizen, Jan Zethof, Robert Whelan, Gert Flik, Marcel Schaaf
FRONTIERS IN IMMUNOLOGY
(2020)
Article
Oncology
Margo Dona, Selma Waaijers, Susan Richter, Graeme Eisenhofer, Jeroen Korving, Sarah M. Kamel, Jeroen Bakkers, Elena Rapizzi, Richard J. Rodenburg, Jan Zethof, Marnix Gorissen, Gert Flik, Peter M. T. Deen, Henri J. L. M. Timmers
Summary: By introducing a protein-truncating germline lesion into the zebrafish sdhb gene using CRISPR/cas9 technology, this study developed the first vertebrate animal model that mimics metabolic effects of SDHB-associated PPGLs. Through functional and metabolomic analyses, the model revealed decreased mitochondrial complex 2 activity and significant succinate accumulation in homozygous sdhb mutant larvae, providing insights into the pathomechanisms behind SDHB-associated PPGLs. This model not only allows for studying the metabolic effects of sdhb disruption during different developmental stages but also aids in identifying novel therapeutic targets in vivo, potentially benefiting pediatric mitochondrial disease caused by loss of the SDHB gene.
ENDOCRINE-RELATED CANCER
(2021)
Article
Biochemistry & Molecular Biology
Cenna Doornbos, Ronald van Beek, Ernie M. H. F. Bongers, Dorien Lugtenberg, Peter. H. M. Klaren, Lisenka E. L. M. Vissers, Ronald Roepman, Machteld M. Oud
Summary: This study developed a robust, standardized approach to accurately diagnose a subset of skeletal ciliopathies. By comparing healthy individuals and patients from three different ciliopathy subgroups, the study illustrated the potential for standardized analysis of cilium phenotypes to discriminate between ciliopathy subgroups.
EUROPEAN JOURNAL OF HUMAN GENETICS
(2021)
Article
Biology
Dylan J. M. Bergen, Qiao Tong, Ankit Shukla, Elis Newham, Jan Zethof, Mischa Lundberg, Rebecca Ryan, Scott E. Youlten, Monika Frysz, Peter I. Croucher, Gert Flik, Rebecca J. Richardson, John P. Kemp, Chrissy L. Hammond, Juriaan R. Metz
Summary: Dermal scales possess a strong osteogenic expression profile similar to bone, enriched in genes favoring collagen matrix growth. Despite differences in developmental processes between scale and endoskeleton, zebrafish scales express a subset of evolutionarily conserved genes relevant to human skeletal diseases.
Article
Medicine, Research & Experimental
Maarten van der Linden, Sangeeta Kumari, Daphne Montizaan, Stephanie van Dalen, Annemarie Kip, Martyn Foster, Inge Reinieren-Beeren, Elsa Neubert, Luise Erpenbeck, Kelsy Waaijenberg, Tirza Bruurmijn, Rezie te Poele, Peter van Zandvoort, Paul Vink, Eric Meldrum, Helmuth van Es, Renato G. S. Chirivi
Summary: This study introduces a novel monoclonal antibody, CIT-013, which inhibits NETosis and reduces tissue NET burden with significant anti-inflammatory consequences. CIT-013 demonstrates high affinity for citrullinated histones and can target autoimmune diseases. The antibody also enhances phagocytosis of NETs and netting neutrophils by macrophages.
Meeting Abstract
Rheumatology
S. van Dalen, M. van den Bosch, A. Blom, P. van der Kraan, T. Vogl, L. Casteilla, P. van Lent
ANNALS OF THE RHEUMATIC DISEASES
(2018)
Article
Computer Science, Information Systems
Mohammed Zuhair Al-Taie, Seifedine Kadry, Adekunle Isiaka Obasa
SOCIAL NETWORK ANALYSIS AND MINING
(2018)
Meeting Abstract
Rheumatology
S. van Dalen, M. van den Bosch, A. Sloetjes, L. Casteilla, A. Blom, P. van Lent
ANNALS OF THE RHEUMATIC DISEASES
(2018)
Article
Psychology, Biological
Umit Yilmaz, Kevser Tanbek
Summary: This study investigated the effects of intracerebroventricular administration of Spexin on the hypothalamus-pituitary-thyroid axis and energy expenditure in rats. The results showed that Spexin reduced food consumption and body weight, increased thyroid hormones, and enhanced energy metabolism.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Kuei-Yu Chien, Yun-Ju Chen, Kuo-Jen Hsu, Chiao-Nan Chen
Summary: This study investigated the effects of a high-protein diet and high-intensity interval training on appetite and weight loss in obese middle-aged individuals. The results showed that consuming a high-protein drink and following a high-protein diet after exercise can reduce post-exercise appetite and the frequency of late-night snacking.
PHYSIOLOGY & BEHAVIOR
(2024)
Review
Psychology, Biological
Melissa Alves Braga Oliveira, Ana Carolina Odebrecht Vergne de Abreu, Debora Barroggi Constantino, Andre C. Tonon, Antoni Diez-Noguera, Fernanda Gaspar Amaral, Maria Paz Hidalgo
Summary: Biological processes in living organisms exhibit strong rhythmicity and are regulated by internal timing systems. Understanding the influence of biological rhythms is crucial for experimental design and reporting.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Yanqun Cao, Hao Chen, Yinna Tan, Xu-Dong Yu, Chuli Xiao, Yin Li, James Reilly, Zhiming He, Xinhua Shu
Summary: There is evidence to suggest that chronic stress impacts neurochemical homeostasis and contributes to mental disorders. This study investigates the therapeutic potential of p-coumaric acid (p-CA), a natural compound found in vegetables and fruits, against stress-associated mental disorders. The findings suggest that p-CA could alleviate cognitive deficits and depression-like behavior in mice exposed to chronic restraint stress (CRS) by regulating the PKA-CREB-BDNF signaling pathway.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Mai O. Spaulding, Jessica R. Hoffman, Grace C. Madu, Magen N. Lord, Caroline Soares Iizuka, Kevin P. Myers, Emily E. Noble
Summary: Food insecurity is associated with obesity and disordered eating behaviors. Studying a rodent model, researchers found that adolescent food insecurity may increase susceptibility to obesity and altered eating behaviors during adulthood.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
K. Oberman, B. L. van Leeuwen, M. Nabben, J. E. Villafranca, R. G. Schoemaker
Summary: The present study investigated the post-operative complications and therapeutic potential of J147 in male Zucker rats, and found that J147 treatment had positive effects on behavioral and metabolic parameters, but did not affect neuroinflammation. The results suggest that a combination of acute and chronic J147 treatment may be optimal for treatment.
PHYSIOLOGY & BEHAVIOR
(2024)
Review
Psychology, Biological
Mathieu Cournoyer, Alice Maldera, Alexandre-Charles Gauthier, Fabien Dal Maso, Marie-Eve Mathieu
Summary: This article provides a comprehensive view of the literature on the effect of different odors on physical activity through a systematic review. It was found that pleasant odors have a positive impact on participants' physical activity. However, better methodological consistency is needed in studies to produce more meaningful results.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Gabriel R. Gilmore, Jeff Dyche
Summary: This study examined sleep, sleep/wake regularity, and cognition in college students diagnosed with depression and using serotonergic antidepressants, comparing them to those without a depression diagnosis. The results showed that students using antidepressants had slightly longer wake after sleep onset and lower sleep efficiency, but these differences were likely not noticed by the participants. There were no differences in sleep regularity or cognition between the two groups.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Erica A. Cross, Kim L. Huhman, H. Elliott Albers
Summary: Social stress plays a significant role in the development of neuropsychiatric disorders and can lead to behavioral deficits such as social withdrawal. This study investigates the impact of social stress on social reward in Syrian hamsters. The results show that subordinate and socially defeated males have reduced motivation for social interactions compared to dominant males. Additionally, winning males exhibit greater activation in the mesolimbic dopamine system compared to losers. In females, there were no differences in social entries between winners and losers, but winning females display more activation in the NAc shell.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Daniel A. R. Cabral, Maria L. M. Rego, Eduardo B. Fontes, Vagner D. O. Tavares
Summary: This study examined the association between body mass index (BMI) and negative emotional states (NES) in men with substance use disorders (SUD) undergoing treatment. The findings showed a positive correlation between BMI and stress, anxiety, and depression. These results suggest that reducing body fat accumulation may contribute to improving mental health in individuals with SUD during recovery.
PHYSIOLOGY & BEHAVIOR
(2024)
Review
Psychology, Biological
Elizabeth Agbor Epse Muluh, Jessica C. McCormack, Yunfan Mo, Michael Garratt, Mei Peng
Summary: This PROSPERO pre-registered systematic review and meta-analysis evaluated the olfactory and gustatory changes in pregnant individuals. The meta-analysis revealed that pregnant individuals performed poorer in odour identification, rated olfactory stimuli to be more intense during the second and third trimester, and had increased pleasantness for sweet taste in the first trimester. No major difference was observed in terms of gustatory functions between pregnant and non-pregnant subjects.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Renee Spiteri Douglas, Mackenzie R. Hartley, J. Renee Yang, Tamara B. Franklin
Summary: The expression of Hdac2 in the hippocampus is associated with social status, while the expression of closely related genes Hdac1 and HDAC2 protein is not associated with social rank in the hippocampus.
PHYSIOLOGY & BEHAVIOR
(2024)